Important Terms

one gene, one enzyme hypothesis

one gene, one polypeptide hypothesis

amino acid

peptide bond

polypeptide

sense codon

degenerate genetic code

synonymous codons

isoaccepting tRNAs

wobble

nonoverlapping genetic code

reading frame

initiation codon

stop (termination or nonsense) codon

universal genetic code

aminoacyl-tRNA synthetase

tRNA charging

initiation factor (IF-1, IF-2, IF-3)

30S initiation complex

70S initiation complex

cap-binding complex (CBC)

aminoacyl (A) site

peptidyl (P) site

exit (E) site

elongation factor Tu (EF-Tu)

elongation factor Ts (EF-Ts)

translocation

elongation factor G (EF-G)

release factor (RF-1, RF-2, RF-3)

polyribosome

mRNA surveillance

nonsense-mediated mRNA decay (NMD)

transfer–messenger RNA (tmRNA)

nonstop mRNA decay

no-go decay

molecular chaperone

signal sequence

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