Section 4.1
What is considered to be the fundamental difference between males and females of most organisms?
How do monoecious organisms differ from dioecious organisms?
Describe the XX-XO system of sex determination. In this system, which is the heterogametic sex and which is the homogametic sex?
How does sex determination in the XX-XY system differ from sex determination in the ZZ-ZW system?
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What is the pseudoautosomal region? How does the inheritance of traits encoded by genes in this region differ from the inheritance of other Y-linked characteristics?
What is meant by genic sex determination?
How does sex determination in Drosophila differ from sex determination in humans?
Give the typical sex-chromosome complement found in the cells of people with Turner syndrome, with Klinefelter syndrome, and with androgen-insensitivity syndrome. What is the sex-chromosome complement of triple-X females?
Section 4.2
What characteristics are exhibited by an X-linked trait?
Explain how Bridges’s study of nondisjunction in Drosophila helped prove the chromosome theory of inheritance.
What characteristics are exhibited by a Y-linked trait?
Section 4.3
Explain why tortoiseshell cats are almost always female and why they have a patchy distribution of orange and black fur.
What is a Barr body? How is it related to the Lyon hypothesis?
For more questions that test your comprehension of the key chapter concepts, go to for this chapter.