Chapter 11. Animation Activity: Levels of Chromatin Structure

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Animation Assessment

Question

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2
Correct. Double-stranded DNA is the primary level of chromatin structure. The most common form of DNA in biological systems is B-form DNA.
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Incorrect. Double-stranded DNA is the primary level of chromatin structure. The most common form of DNA in biological systems is B-form DNA.

Question

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2
Correct. The diameter of B-form DNA is 2 nm. Individual base pairs are 0.34 nm apart, and one complete turn of the double helix is 3.4 nm encompassing 10 base pairs.
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Incorrect. The diameter of B-form DNA is 2 nm. Individual base pairs are 0.34 nm apart, and one complete turn of the double helix is 3.4 nm encompassing 10 base pairs.

Question

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2
Correct. The nucleosome consists of double-stranded DNA wrapped nearly two times around a protein core consisting of two molecules each of histone proteins H2A, H2B, H3, and H4.
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Incorrect. The nucleosome consists of double-stranded DNA wrapped nearly two times around a protein core consisting of two molecules each of histone proteins H2A, H2B, H3, and H4.

Question

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2
Correct. Histone H1 clamps DNA that is entering and leaving the nucleosome to form the chromatosome. Histone H1 is not a core nucleosome protein.
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Incorrect. Histone H1 clamps DNA that is entering and leaving the nucleosome to form the chromatosome. Histone H1 is not a core nucleosome protein.

Question

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2
Correct. The average repeating unit of DNA in the chromatosome (beads on a string) structure is about 200 bp.
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Incorrect. The average repeating unit of DNA in the chromatosome (beads on a string) structure is about 200 bp.

Question

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2
Correct. Nucleosomes fold on themselves to create the 30 nm fiber based on histone interactions. In particular, histone H1 is important in creating the 30 nm fiber.
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Incorrect. Nucleosomes fold on themselves to create the 30 nm fiber based on histone interactions. In particular, histone H1 is important in creating the 30 nm fiber.

Question

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2
Correct. Interphase DNA consists of 30 nm loops of DNA with a length of approximately 300 nm tethered to the nuclear scaffold creating a fiber with a width of approximately 250 nm.
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Incorrect. Interphase DNA consists of 30 nm loops of DNA with a length of approximately 300 nm tethered to the nuclear scaffold creating a fiber with a width of approximately 250 nm.

Question

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2
Correct. Mitotic chromosomes consist of tight helical coiling of the 250 nm fiber present in interphase chromatin.
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Incorrect. Mitotic chromosomes consist of tight helical coiling of the 250 nm fiber present in interphase chromatin.

Question

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2
Correct. Although the length of linker DNA is variable in a chromosome (in fact, this may be an important way to regulate gene expression), the average length of linker DNA (the DNA between chromatosomes) is 45 bp.
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Incorrect. Although the length of linker DNA is variable in a chromosome (in fact, this may be an important way to regulate gene expression), the average length of linker DNA (the DNA between chromatosomes) is 45 bp.

Question

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2
Correct.
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Incorrect.