Articles on ethical issues in genetics are preceded by an asterisk.

Ben-Yehuda, S., D. Z. Rudner, and R. Losick. 2003. RacA, a bacterial protein that anchors chromosomes to the cell poles. Science 299:532–536.

Presents information about proteins that play a role in the separation of chromosomes in bacterial reproduction.

Bouck, D. C., A. P. Joglekar, and K. S. Bloom. 2008. Design features of a mitotic spindle: balancing tension and compression at a single microtubule kinetochore interface in budding yeast. Annual Review of Genetics 42:335–359.

A comprehensive review of the molecular basis of chromosome separation.

R2

Caudron, M., G. Bunt, P. Bastiaens, et al. 2005. Spatial coordination of spindle assembly by chromosome-mediated signaling gradients. Science 309:1372–1376.

Reports that formation of the spindle is mediated by interactions between the chromosomes and gradients of small molecules.

Fogel, M. A., and M. K. Waldor. 2009. A dynamic, mitotic-like mechanism for bacterial chromosome segregation. Genes & Development 20:3269–3282.

Discusses mechanism of DNA separation during cell reproduction in the bacterium Vibrio cholerae.

Glotzer, M. 2005. The molecular requirements for cytokinesis. Science 307:1735–1739.

A review of the molecular events in animal cytokinesis.

Jarrell, K. F., D. P. Bayley, J. D. Correia, et al. 1999. Recent excitement about archaea. BioScience 49:530–541.

An excellent review of differences among eubacteria, archaea, and eukaryotes.

King, R. W., P. K. Jackson, and M. W. Kirschner. 1994. Mitosis in transition. Cell 79:563–571.

A good review of how the cell cycle is controlled.

Kitajima, T. S., S. A. Kawashima, and Y. Watanabe. 2004. The conserved kinetochore protein shugoshin protects centromeric cohesion during meiosis. Nature 427:510–517.

Reports that shugoshin protects centromeric cohesin during anaphase I of meiosis.

Koshland, D. 1994. Mitosis: back to basics. Cell 77:951–954.

A review of research on mitosis and chromosome movement.

Kotwaliwale, C., and S. Buggins. 2006. Microtubule capture: a concerted effort. Cell 127:1105–1108.

A short review of kinetochore proteins and their participation in attachment to spindle fibers.

Magidson, V., C. B. O’Connell, J. Lončarek, et al. 2011. The spatial arrangement of chromosomes during prometaphase facilitates spindle assembly. Cell 146:555–567.

A research article on the process by which the spindle assembles and chromosomes become bioriented.

Mogilner, A., R. Wollman, G. Civelekogul-Scholey, et al. 2006. Modeling mitosis. Trends in Cell Biology 16:88–96.

A review of the different parts of the protein machine that brings about the segregation of sister chromatids in mitosis.

Morgan, D. O. 1995. Principles of CDK regulation. Nature 34:131–134.

An excellent short review of cell-cycle control.

Musaccio, A. 2011. Travel notes from the equatorial circle. Cell 146:499–501.

A short review of recent research on chromosome segregation in mitosis and meiosis.

Nasmyth, K. 2002. Segregating sister genomes: the molecular biology of chromosome separation. Science 297:559–565.

A very good and readable review of advances in our understanding of the molecular biology of sister-chromatid and homologous-chromosome separation in mitosis and meiosis.

Page, S. L., and R. S Hawley. 2003. Chromosome choreography: the meiotic ballet. Science 301:785–789.

An excellent review of the molecular biology of key events in mitosis and meiosis. See other articles in this issue of Science on bacterial chromosome replication and separation, prokaryotic chromosomes and disease, and eukaryotic chromosome evolution.

Pluta, A. F., A. M. MacKay, A. M. Ainsztein, et al. 1995. Centromere: the hub of chromosome activities. Science 270:1591–1594.

An excellent review of centromere structure and function.

Rogers, G. C., S. L. Rogers, T. A. Schwimmer, et al. 2004. Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase. Nature 427:364–370.

Reports that tubulin is removed from both ends of the spindle fiber in anaphase.

Rothfield, L., S. Justice, and J. Garcia-Lara. 1999. Bacterial cell division. Annual Review of Genetics 33:423–428.

A comprehensive review of how bacterial cells divide.

Uhlmann, F., F. Lottespeich, and K. Nasmyth. 1999. Sister chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1. Nature 400:37–42.

Reports that cleavage of cohesin protein has a role in chromatid separation.

Zickler, D., and N. Kleckner. 1999. Meiotic chromosomes: integrating structure and function. Annual Review of Genetics 33:603–754.

A review of the structure and function of chromosomes in meiosis.