Articles on ethical issues in genetics are preceded by an asterisk.

Baker, T. A., and S. H. Wickner. 1992. Genetics and enzymology of DNA replication in Escherichia coli. Annual Review of Genetics 26:447–477.

A detailed review of replication in bacteria.

Crabbe, L., R. E. Verdun, C. I. Haggblom, and J. Karlseder. 2004. Defective telomere lagging strand synthesis in cells lacking WRN helicase activity. Science 306:1951–1953.

Reports evidence that people with Werner syndrome suffer from a defect in telomere-length maintenance.

Echols, H., and M. F. Goodman. 1991. Fidelity mechanisms in DNA replication. Annual Review of Biochemistry 60:477–511.

A review of error-avoidance mechanisms in replication.

Frick, D. N., and C. C. Richardson. 2000. DNA primases. Annual Review of Biochemistry 70:39–80.

An excellent and detailed review of DNA primases, which are essential to the replication process.

Garg, P., and P. M. J. Burgers. 2005. DNA polymerases that propagate the eukaryotic DNA replication fork. Critical Reviews in Biochemistry and Molecular Biology 40:115–128.

An excellent review of the action of DNA polymerases that act at the replication fork in eukaryotes.

Greider, C. W., and E. H. Blackburn. 1996. Telomeres, telomerase, and cancer. Scientific American 274(2): 92–97.

A readable account of telomeres, how they are replicated, and their role in cancer.

R8

Groth, A., A. Corpet, A. J. Cook, et al. 2007. Regulation of replication fork progression through histone supply and demand. Science 318:1928–1931.

A research report showing that histone chaperones participate in supplying new nucleosomes after replication.

Groth, A., W. Rocha, A. Verreault, et al. 2007. Chromatin challenges during DNA repair. Cell 128:721–733.

A review of how nucleosomes are replicated and epigenetic marks are maintained through replication.

Haber, J. E. 1999. DNA recombination: the replication connection. Trends in Biochemical Science 24:271–276.

Describes the role of the establishment of replication forks in recombination.

Heidinger, B. J., J. D. Blount, W. Boner, et al. 2012. Telomere length in early life predicts lifespan. Proceedings of the National Academy of Sciences of the United States of America 109:1743–1748.

Report of research on zebra finches showing that birds with longer telomeres live longer.

Hübscher, U., H. Nasheuer, and J. E. Syväoja. 2000. Eukaryotic DNA polymerases: a growing family. Trends in Biochemical Science 25:143–147.

An excellent review of the increasing number of different DNA polymerases found in eukaryotic cells and their functions.

Johnson, A., and M. O’Donnell. 2005. Cellular DNA replicases: components and dynamics at the replication fork. Annual Review of Biochemistry 74:283–315.

Reviews the replication machinery, with particular emphasis on the DNA polymerase clamp and the clamp loader.

Kornberg, A., and T. A. Baker. 1992. DNA Replication, 2d ed. New York: W. H. Freeman.

A good reference on DNA replication by one of the world’s foremost authorities on the subject.

Koster, D. A., K. Palle, E. S. Bot, et al. 2007. Antitumour drugs impede DNA uncoiling by topoisomerase I. Nature 448:213–217.

A research report showing that the camptothecin anticancer compounds work by preventing topoisomerase I from reducing supercoiling during replication.

Kowalczykowski, S. C. 2000. Initiation of genetic recombination and recombination-dependent replication. Trends in Biochemical Science 25:156–164.

A review of the role of replication processes in recombination.

Lee, C., B. Hong, J. M. Choi, et al. 2004. Structural basis for inhibition of the replication licensing factor Cdt1 by Geminin. Nature 430:913–916.

A report on the role of Cdt1 and Geminin in replication licensing.

McCulloch, S. D., and T. A. Kunkel. 2008. The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases. Cell Research 18:148–161.

A review of the action of DNA polymerases in eukaryotes.

Nossal, N. C. 1983. Prokaryotic DNA replication systems. Annual Review of Biochemistry 53:581–615.

A good review of replication in bacteria.

Pursell, Z. F., I. Isoz, E. Lundström, et al. 2007. Yeast DNA polymerase epsilon participates in leading-strand DNA replication. Science 317:127–130.

A research report providing evidence that polymerase ε in eukaryotes carries out leading-strand synthesis.

Radman, M., and R. Wagner. 1988. The high fidelity of DNA duplication. Scientific American 259(2): 40–46.

A very readable account of how the accuracy of DNA replication is ensured.

Reyes-Lamonthe, R., D. J. Sherrat, and M. C. Leake. 2010. Stoichiometry and architecture of active DNA replication machinery in Escherichia coli. Science 328:498–501.

Research suggesting that the E. coli replication machinery includes three molecules of the replication enzyme, not two as has generally been assumed.

Robinson, N. P., I. Dionne, M. Lundgren, et al. 2004. Identification of two origins of replication in the single chromosome of the archaeon Sulfolobus solfataricus. Cell 116:25–38.

Reports on research finding that an archaean has two origins of replication.

Roy, R., A. G. Kozlov, T. M. Lohman, et al. 2009. SSB protein diffusion on single-stranded DNA stimulates RecA filament formation. Nature 461:1092–1097.

Research demonstrating that single-strand binding proteins move along the DNA template during replication.

Shay, J. W., and W. E. Wright. 2004. Telomeres in dyskeratosis congenita. Nature Genetics 36:437–438.

A brief summary of the role of telomeres in the genetic disease dyskeratosis congenita.

Stahl, F. W. 1994. The Holliday junction on its thirtieth anniversary. Genetics 138:241–246.

A brief history of the Holliday model of recombination and its relevance.

Tomás-Loba, A., I. Flores, P. J. Fernández-Marcos, et al. 2008. Telomerase reverse transcriptase delays aging in cancer-resistant mice. Cell 135:609–622.

Presents evidence that the activation of telomerase affects aging.

Verdun, R. E., and J. Karlseder. 2007. Replication and protection of telomeres. Nature 447:924–930.

A good review of the role of telomeres and their replication.

Waga, S., and B. Stillman. 1998. The DNA replication fork in eukaryotic cells. Annual Review of Biochemistry 67:721–751.

Summarizes the components of the replication machinery and the process of DNA synthesis that takes place at the replication fork in eukaryotic cells.

West, S. C. 1992. Enzymes and molecular mechanisms of genetic recombination. Annual Review of Biochemistry 61:603–640.

An excellent but detailed review of recombination at the molecular level.

Zakian, V. A. 1995. Telomeres: beginning to understand the ends. Science 270:1601–1606.

A review article describing telomeres and how they are replicated.