11.2 Stress and Your Health

CONNECTIONS

We introduced the fight-or-flight response to stressors in Chapter 2. The sympathetic nervous system is a division of the autonomic nervous system, which regulates the body’s involuntary activity (such as digestion and the beating of the heart). Here, we will learn how this automatic activity may relate to illness.

image TROUBLE UNDERCOVER  Meet Sergeant Michelle, a long-time veteran of a police department in a large city at the foot of the Rocky Mountains. Michelle currently works in internal affairs investigating potential policy violations by police officers—a highly stressful position given that the outcome of such investigations can lead to the suspension or termination of fellow officers. But it doesn’t match the intense, fear-for-your-life type of stress that Michelle experienced at other points in her career, like the time her cover was nearly blown in an operation to bust crack-cocaine dealers. Posing as a buyer, Michelle walked into a house where a suspected dealer was selling. One of the men who happened to be hanging out in the house gave her a funny look, and she instantly realized that he recognized her as a police officer. Fortunately, the man did not give her away (who knows what the dealer would have done had her identity been revealed), and Michelle escaped the situation unscathed. But we can only imagine what she must have felt at that moment.

Faced with the prospect of being gunned down by a drug dealer, Michelle most likely experienced the sensations associated with the fight-or-flight response, such as increased pulse, breathing rate, and mental alertness. A coordinated effort of the sympathetic nervous system and the endocrine system, the fight-or-flight reaction primes the body to respond to danger, either by escaping (bolting out of the crack house, as in Michelle’s case) or confronting the threat head-on (defending herself against a physical attack). Let’s take a closer look at this survival mechanism.image

Fight or Flight

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LO 4 Identify the brain and body changes that characterize the fight-or-flight response.

CONNECTIONS

In Chapter 2, we introduced the parasympathetic nervous system, which is responsible for the “rest-and-digest” process following activation of the fight-or-flight response. The parasympathetic nervous system works with the sympathetic nervous system to prepare us for crises and then to calm us when danger has passed.

When faced with a threatening situation, portions of the brain, including the hypothalamus, activate the sympathetic nervous system, which leads to the secretion of catecholamines, such as epinephrine and norepinephrine. These hormones cause heart rate, blood pressure, respiration, and blood flow to the muscles to increase. Meanwhile, digestion slows and the pupils dilate.

Physiological responses prepare us for an emergency by efficiently managing the body’s resources. Once the emergency has ended, the parasympathetic system reverses these processes by reducing heart rate, blood pressure, and so on. If a person is exposed to a threatening situation for long periods of time, the fight-or-flight system remains active. This in turn can have detrimental effects on health (Shonkoff et al., 2012), an issue we will explore later.

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Selye’s Stages
Endocrinologist Hans Selye proposed that the body passes through a predictable sequence of changes in response to stress. Selye’s general adaptation syndrome includes three phases: the alarm stage, the resistance stage, and the exhaustion stage.
Bettmann/CORBIS

LO 5 Outline the general adaptation syndrome (GAS).

general adaptation syndrome (GAS) A specific pattern of physiological reactions to stressors that includes the alarm stage, resistance stage, and exhaustion stage.

GENERAL ADAPTATION SYNDROME Hans Selye, introduced earlier in the chapter, identified police work “as likely the most stressful occupation in the world” (according to Violanti, 1992, p. 718). One of the first to suggest the human body responds to stressors in a predictable way, Selye (1936) described a specific pattern of physiological reactions, which he called the general adaptation syndrome (GAS).

According to this theory, the body passes through three stages (Infographic 11.2). The first is the alarm stage, or the body’s initial response to a threatening situation, similar to the fight-or-flight response. Arousal increases, and the body prepares to deal with the threat. Following the alarm stage is the resistance stage. During this period, the body maintains a high level of arousal (though not as high as that of the alarm stage), but with a decreased response to new stressors. Under such intense physiological demands, the body simply cannot address any new threatening situations that might arise. According to Selye, this is when some people start to show signs of diseases of adaptation, such as hypertension and arthritis (Selye, 1953; Selye & Fortier, 1950). If the threat remains and the person can no longer adapt, Selye suggested that the body then moves into the exhaustion stage. At this point, the body’s resources become depleted, resulting in vulnerability to illnesses, physical exhaustion, and even death.

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INFOGRAPHIC 11.2

Figure 11.2: INFOGRAPHIC 11.2
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Credit: Firefighter, Thinkstock; Firefighter crouching, Alan Bailey/Shutterstock; Male fire fighter with smoky background, Colin Anderson/age fotostock

LO 6 Describe the function of the hypothalamic–pituitary–adrenal (HPA) system.

Synonyms
hypothalamic–pituitary–adrenal (HPA) system hypothalamic–pituitary–adrenal axis (HPA axis)

HYPOTHALAMIC–PITUITARY–ADRENAL SYSTEM Overseeing the sympathetic nervous system’s response to stress is the hypothalamic–pituitary–adrenal (HPA) system (Infographic 11.2). This HPA system helps to maintain balance in the body by directing not only the sympathetic nervous system, but also the neuroendocrine and immune systems (Ben-Zvi, Vernon, & Broderick, 2009). The immune system defends the body from bacteria, viruses, and other types of invaders by deploying cells and chemicals to confront these threats. When a stressful situation arises, the hypothalamus initiates a cascade of responses by alerting the pituitary gland, which then sends signals to the adrenal cortex, which in turn orders the secretion of corticosteroids, such as cortisol. These hormones summon the immune system to fend off a threat and reduce the amount of energy used for nonessential activities (that is, those not associated with the threat), such as digestion and bladder control. The HPA system responds to a stressor in the same way it would to a pathogen—by mobilizing a defense response. You might say it’s working overtime. How do you think this affects a person’s health?

Synonyms
health psychology behavioral medicine
B lymphocytes B cells
T lymphocytes T cells

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Psychologists have been exploring this issue for decades, trying to determine how stress influences human health. Early in the 1960s, the field of health psychology began to gather momentum, exploring the biological, psychological, and social factors that contribute to health and illness. Health psychology seeks to explain how food choices, social interactions, and living environments affect our predisposition to illness. Researchers in this field contribute to health education, helping people develop positive eating and exercise habits. They conduct public policy research that influences health-related guidelines. Health psychologists also study the impact of personality factors, coping style, cognitive appraisal, poverty, culture, social support, and religion—all topics addressed in this chapter.

Is Stress Making You Sick?

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The Immune System
Our immunity derives from a complex system involving structures and organs throughout the body that support the work of specialized cell types to keep us healthy.
Man: B2M Productions/Getty Images; T lymphocytes & B lymphocytes: Steve Gschmeissner/Science Source; Natural killer cells & macrophages: Eye of Science/Science Source

LO 7 Explain how stressors relate to health problems.

lymphocyte Type of white blood cell produced in the bone marrow whose job is to battle enemies such as viruses and bacteria.

Before we explore the connection between stress and illness, we must understand how the body deals with illness in the first place. Let’s take a side trip into introductory biology and learn about the body’s main defense against disease—the immune system (Figure 11.3). The immune system is made up of the spleen, lymph nodes, and bone marrow. When disease-causing invaders threaten the body, the immune system deploys a special army of white blood cells called lymphocytes. Lymphocytes are produced in bone marrow, and their job is to battle enemies such as viruses and bacteria. When the body is expending its resources to deal with an ongoing stressor, the immune system is less powerful, and the work of the lymphocytes is compromised.

Like a platoon of soldiers, the immune system has a defense team to fight off invaders. Should the intruder(s) get past the skin, the macrophages (“big eaters”) are ready to attack. These cells hunt and consume invaders as well as worn-out cells in the body. Cells that have been affected by invaders, such as viruses and cancer, are the targets of natural killer cells (NK cells), which inject compromised cells with a deadly chemical. In addition, NK cells release a protein that prevents the infection from spreading to other cells. In some cases, the body must call on its “special ops” teams. These are the B lymphocytes and T lymphocytes. The B lymphocytes mature in the bone marrow and produce antibodies that chemically inhibit bacteria. The T lymphocytes mature in the thymus and play an integral role in fighting cancer, viruses, and other disease-causing agents that the B lymphocytes have not been successful in warding off (Straub, 2012).

Earlier we mentioned that stressors are correlated with health problems. But how exactly do stressors such as beliefs and attitudes affect the physical body? In other words, what is the causal relationship between stressors and illness? Let’s address this question by examining some illnesses thought to be closely linked to stressors (Cohen, Miller, & Rabin, 2001).

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Battling Stress
A group of Marines practice patrolling techniques as part of their combat training. Long-term stressors such as military deployment are associated with declines in NK cells, which help the body fight infections.
Scott Olson/Getty Images

GASTRIC ULCERS AND STRESSORS Gastric ulcers have long been thought to be associated with stress, but the nature of this link has not always been clear. For many years, it was believed that stress alone caused gastric ulcers, but researchers then started to suspect other culprits. They found evidence that the bacterium H. pylori plays an important role. This does not mean that H. pylori is always to blame, however. Some people who carry the bacteria never get ulcers, while others develop ulcers in its absence. It seems that many factors influence the development of ulcers, among them tobacco use, family history, and excess gastric acid (Fink, 2011).

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CANCER AND STRESSORS Cancer has also been associated with stress, both in terms of risk and development. Specifically, stress has been linked to the suppression of T lymphocytes and NK cells, which help monitor immune system reactions to the invasion of developing tumors. When a person is exposed to stressors, the body is less able to mount an effective immune response, which increases the risk of cancer (Reiche, Nunes, & Morimoto, 2004).

In the United States and other Western countries, breast cancer is the greatest cancer risk for women, and some evidence suggests it is associated with stress. In a meta-analysis of 26 studies examining the association between life events and risk for breast cancer, death of a spouse was found to be modestly linked to the development of breast cancer; however, no other life events were related to increased risk (Duijts, Zeegers, & Borne, 2003). Other studies have found no association between life events and breast cancer risk (Roberts, Newcomb, Trentham-Dietz, & Storer, 1995).

CONNECTIONS

In Chapter 6, we discussed the malleability of memory. Problems may arise when study participants are asked to remember events and illnesses from the past. Here we are describing a prospective study, which does not require participants to retrieve information from the distant past, thus reducing opportunities for error.

Stress has been correlated with other types of cancer, though not always in the expected direction. One group of researchers examined the relationship between chronic daily stressors and the development of colorectal cancer using a prospective study in which nearly 12,000 Danes (who had never been diagnosed with colorectal cancer) were followed for 18 years (Nielsen et al., 2008). The researchers noted some surprising findings, particularly with respect to females. Women who reported higher levels of “stress intensity” and “daily stress” were less likely to develop colon cancer during the course of the study. In contrast, men with “high stress intensity” experienced higher levels of rectal cancer, although this association was not considered to be strong because only a small number actually developed this kind of cancer. The authors suggested that a variety of physiological, mental, and behavioral factors (for example, sex hormones, burnout, and increased alcohol intake) were involved in the relationship between high stress and lower rates of colon cancer in the women.

Why can’t researchers agree on the link between cancer and stressors? Part of the problem is that studies are focusing on stressors of different durations. Short- and long-term stressors have distinct effects on the immune system, and thus its ability to combat cancer (Segerstrom & Miller, 2004). For short-lived stressors such as midterm exams, public speaking, and other activities lasting between 5 and 100 minutes, the body responds by increasing the number of NK cells and deploying other immune cells where needed. In other words, short-term stressors tend to augment immune functioning. The situation is quite different with long-term stressors such as military deployment or caring for someone with dementia, which are associated with decreases in NK cells. In order to appreciate the complex relationship between stress, immune function, and cancer, we must also consider biopsychosocial influences on a person’s response to stressors. Factors such as age, medical history, social support, and mental health can mediate the link between stressors and cancer (Reiche et al., 2004; Segerstrom & Miller, 2004).

CARDIOVASCULAR DISEASE AND STRESSORS The same is true for the relationship between stressors and cardiovascular disease. Dimsdale (2008) noted that over 40,000 citations popped up in a medical database when the search terms were “stress” and “heart disease.” What constitutes a stressor in this context? Earthquakes, unhappy marriages, and caregiving burdens are just a few stressors associated with a variety of outcomes or vulnerabilities, ranging from abnormalities in heart function to sudden death. Earlier we discussed socioeconomic status and stress; it turns out that both of those variables are factors in cardiovascular disease. Joseph and colleagues reported fivefold higher odds of experiencing “cardiometabolic events” (within 5 years) for people who became unemployed as a result of Hurricane Katrina, a devastating natural disaster that occurred in 2005 (Joseph, Matthews, & Myers, 2013, March 25). The faster people get support to decrease “socioeconomic disruptions” related to a disaster, the better their health outcomes.

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Staying Alive
Paramedics transfer a patient from ambulance to emergency room. The patient is clearly experiencing a health crisis, but the paramedics face their own set of health risks. Working odd hours, not getting enough exercise, eating poorly, and dealing with the ongoing stresses of paramedic work make it challenging to stay healthy.
Juan Manuel Silva/age footstock

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Other stressors have also been linked to heart disease. “Social-evaluative threats,” or concerns about being judged by others (about physical appearance or behaviors in a social context, for example), are associated with increases in blood pressure and consequently elevated risk of heart disease (Smith, Birmingham, & Uchino, 2012). One model suggests that increased job stress can put people at greater risk for developing coronary heart disease, particularly those who perceive a significant degree of job “strain” resulting from high demands, lack of control, and other factors (Ferris, Kline, & Bourdage, 2012).

The mechanisms of the causal relationship between stressors and cardiovascular disease are not totally understood (Straub, 2012). However, we do know that an increase of fatty deposits, inflammation, and scar tissue within artery walls, that is, atherosclerosis, is a dangerous risk factor for stroke and heart disease (Go et al., 2013). With this type of damage, blood flow in an artery may become blocked or reduced. Researchers are not sure exactly how atherosclerosis starts, but one theory suggests that it begins with damage to the inner layer of the artery wall, which may be caused by elevated cholesterol and triglycerides, high blood pressure, and cigarette smoke (American Heart Association, 2012). It is important to note that stressors cannot be shown to cause changes in cardiovascular health (Dimsdale, 2008). Although there is a clear correlation between biopsychosocial stressors and cardiovascular disease, we cannot say with certainty that these stressors are responsible (Ferris et al., 2012).

Stress and Substances

Stress often exerts its harmful effects indirectly (Cohen et al., 2001). When faced with stressors, we may sleep poorly, eat erratically, and perhaps even drink more alcohol. These behavioral tendencies can lead to significant health problems (Benham, 2010; Ng & Jeffery, 2003).

SMOKING AND STRESS In Chapter 4, on consciousness, we described how drugs are used to alleviate pain, erase memories, and toy with various aspects of consciousness. But a discussion of drugs is also in order here, because many people use drugs to ease stress. Smokers report that they smoke more cigarettes in response to stressors, as they believe it improves their mood. The association between lighting up and feeling good is one reason smokers have such a hard time quitting (Lerman & Audrain-McGovern, 2010). One study found that when participants were forced to abstain from smoking for some time (a half day, for example), their mood did improve when they finally puffed on a cigarette. However, this was the only stressful condition of the study in which smoking heightened mood; the effect was not observed when participants were made to prepare for a public-speaking task, for example (Perkins, Karelitz, Konklin, Sayette, & Giedgowd, 2010). Such findings are inconsistent with the self-reports of smokers, who claim that they smoke to feel better in a variety of stressful situations.

CONNECTIONS

In Chapter 4, we discussed the concept of physiological dependence and tolerance. When we use drugs, such as nicotine, they alter the chemistry of the brain and body. Over time, the body adapts to the drug and therefore needs more and more of it to create the original effect.

How do we get people to kick a habit that is perceived as so pleasurable? One effective way is to meet them where they are, rather than taking a one-size-fits-all approach (Mahoney, 2010; Prochaska, Velicer, Prochaska, Delucchi, & Hall, 2006). In other words, we should recognize that not all smokers need the same type of help. Some need assistance with smoking only; others engage in additional risky behaviors, like eating high-fat diets or getting too much sun. First-time quitters need different interventions than those who have quit before and relapsed. And success is more likely when the benefits and risks of smoking are made clear. For example, smokers often believe quitting will make them gain weight; therefore, they continue to smoke and don’t give enough thought to the serious risks of smoking. Gender is another important consideration, as women seem to be more susceptible to anxiety, depression, and perceived stressors when they fail to quit. Men, on the other hand, seem more vulnerable to cigarette cravings (Nakajima & al’Absi, 2012). This leads us to an important point: Do not underestimate the biology of nicotine addiction. Through tolerance, the body becomes dependent on the nicotine; the more you use it, the more of it you need to get the same effect.

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It’s Not Medicine
Some people turn to alcohol and other drugs for stress relief, but the self-medication approach is not effective. A better strategy might be jogging in the park, laughing with a friend, or doing some deep breathing exercises.
Image Source/Alamy

ALCOHOL AND STRESS Much the same could be said for alcohol, another drug frequently used to “take the edge off,” or counteract, the unpleasant feelings associated with stress. Perhaps you know someone who “needs” a drink to relax after a rough day. Psychologists explain this type of behavior with the self-medication hypothesis, which suggests that people turn to drugs and alcohol to reduce anxiety (Swendsen et al., 2000).

Teenagers, in particular, appear to rely on alcohol to cope with daily hassles (Bailey & Covell, 2011). Adolescents frequently face disagreements with family members, teachers, and peers. They may worry about how they look and whether they are succeeding in school. We need to help adolescents find new and more “healthy” ways to handle these hassles. This means providing more support in schools, and perhaps educating teachers and counselors about the tendency to self-medicate with drugs and alcohol. Later we will discuss some positive coping strategies for teens and adults alike, but first let’s see how some people seem to thrive under stress.

image ADRENALINE JUNKIES  What lures a person into an EMS career? The reward of alleviating human suffering is “incredible,” according to Kehlen. Imagine walking into the home of a diabetic who is lying on the floor, unconscious and surrounded by trembling family members. You insert an IV line into the patient’s vein and deliver D50, a dextrose solution that increases blood sugar. In a few moments, the person is awake as if nothing happened. The family is ecstatic; you have saved their loved one from potential brain damage or death. “People that like to do selfless acts, I think, are made for this job,” Kehlen says. And for those who enjoy a good challenge, both physical and mental, an EMS career will not disappoint. Try working for 24 hours in a row, making life-and-death decisions, hoisting heavy bodies onto stretchers, and crouching over patients until your joints burn.

But there appears to be something else drawing people into the EMS profession. You might call it the “adrenaline junkie” factor. Ever since Kehlen was a small boy, he enjoyed a certain amount of risk taking. He was the kid who fearlessly scaled the monkey bars and leaped off the jungle gym, and many of his colleagues claim they were the same way. “All of us probably thought we were 10 feet tall and made of steel,” Kehlen says, careful to note that “daring” is not the same as “reckless.” One must be calculating when it comes to determining what risks are worth taking.

The adrenaline junkie quality is also apparent in some police officers, according to Sergeant Michelle. An officer patrolling a city beat probably experiences the so-called adrenaline rush at least a few times per week. “When a hot call comes in, anyone worth their salt wants to go,” Sergeant Michelle explains (“hot call” meaning anything full of excitement and drama, like a robbery in progress).

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Is there really some common adrenaline junkie tendency among police officers, EMS providers, and other first responders? That remains an open question. We do know, though, that first responders are frequently exposed to highly stressful events (Anderson, Litzenberger, & Plecas, 2002; Gayton & Lovell, 2012). With all this exposure to violence and trauma, how do the body and mind hold up? The answer is probably different for each individual, but constant stress certainly has the potential to erode health and well-being.image

Too Much Cortisol

LO 8 List some consequences of prolonged exposure to the stress hormone cortisol.

Earlier we discussed the stress hormone cortisol, which plays an important role in mobilizing the body to react to threats and other stressful situations. Cortisol is useful if you are responding to immediate danger, like a raging fire or ruthless assailant. However, you don’t want cortisol levels to remain high for long. Both body and brain are impacted when the cortisol system flips into overdrive.

CORTISOL AND KIDS The negative effects of stress are apparent very early in life—even before birth, in some cases. Increased levels of cortisol in mother and fetus can cause a variety of problems during pregnancy and after birth, including spontaneous abortion, preeclampsia, heart defects, and preterm delivery (Mulder et al., 2002). Infants born to mothers subjected to natural disasters, trauma, and other extreme stressors are more likely to be born prematurely, have low birth weights, exhibit behavioral difficulties, and perhaps even show problems with cognitive development (Davis & Sandman, 2010; Tollenaar, Beijers, Jansen, Riksen-Walraven, & De Weerth, 2011). Prenatal stressors have also been reported to be associated with fussing and crying, but this link might be indirect (Field & Diego, 2008); such temperamental difficulties could be due to preterm birth (Baibazarova et al., 2013).

Now consider the types of stressors some preschool children confront every day. Research shows that conflicts at home can increase cortisol levels in children (Slatcher & Robles, 2012). Verbal exchanges such as the child exclaiming, “No! I don’t want to!” and parents saying, “You are going to shut your mouth and be quiet!” are exactly the types of conflicts associated with increased cortisol levels. Cortisol activity may help explain why exposure to conflict during childhood seems to pave the way for health problems (Slatcher & Robles, 2012). Clearly, cortisol plays a role in early development. But how does this stress hormone affect adults?

CONNECTIONS

In Chapter 6, we presented the concept of working memory, which refers to how we actively maintain and manipulate information in short-term memory. Here, we see how these activities can be impacted by stressful situations.

CORTISOL ON THE JOB High cortisol levels can have life-or-death consequences, particularly for workers who make on-the-spot safety decisions. In one study, researchers had police officers participate in a realistic simulation of being targeted by shooters. Not only did the officers’ cortisol levels rise, but the functioning of their working memory decreased (Taverniers, Smeets, Van Ruysseveldt, Syroit, & von Grumbkow, 2011). Can you imagine the implications of being in a dangerous situation with impaired working memory? Think of the last time you were really afraid, and how difficult it was to think clearly. Your working memory was probably compromised.

Other research suggests that heightened cortisol levels may have the opposite effect. When police officers had to make threat-related decisions in a video simulation, they were better able to discern whether an individual was armed when their cortisol levels were high. But this accuracy increased when the officer faced a simulation involving a Black suspect, and decreased when the suspect was White. This finding was the same for the White officers and minority officers participating in the study. The researchers concluded that higher cortisol levels, which were caused by the stressful situation, resulted in “heightened vigilance for danger” (Akinola & Mendes, 2012, p. 172). Apparently, the perceived threat of Black men was greater, which is consistent with what social psychologists have learned about the conscious and unconscious reactions many people have to racial minorities (Chapter 14).

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psychoneuroimmunology (sī-kō-'n(y)u̇r-ō-'im-yə-'nä-lə-jē) The field that studies the relationships among psychological factors, the nervous system, and immune system functioning.

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Performance Anxiety
Heightened cortisol levels can help or hinder a person studying for a math test. For people with “higher working memory” and low math anxiety, cortisol seems to boost performance, but it has the opposite effect when math anxiety is high (Mattarella-Micke, Mateo, Kozak, Foster, & Beilock, 2011).
Alejandro Rivera/Getty Images

PSYCHONEUROIMMUNOLOGY We have now discussed some of the effects of short- and long-term stressors. You know that a spurt of cortisol steps up immunity and prepares the body to confront a threat. You also know that if cortisol levels remain high for prolonged periods (as occurs with chronic stressors), the immune system may not function at an optimal level. We discussed how this affects one’s risk for developing gastric ulcers, cancer, and heart disease, but the list of negative health effects is much longer. According to a meta-analysis of over 300 studies, chronic stressors were found to be associated with problematic immune system responses, which may increase the risk for various illnesses involving inflammation, including asthma, allergies, multiple sclerosis, and rheumatoid arthritis (Segerstrom & Miller, 2004). The exact nature of these relationships is yet to be determined, but researchers are working hard to uncover them, especially for people who are aging and who have vulnerable immune systems (Cohen et al., 2001). It is an exciting time for those who specialize in the field of psychoneuroimmunology (sī-kō-'n(y)u̇r-ō-'im-yə-'nä-lə-jē), which examines the relationships among psychological factors (such as coping, emotions, and beliefs), the nervous system, and the functioning of the immune system.

The field of health psychology, which draws on the biopsychosocial model and psychoneuroimmunology, has shed light on the complex relationship between stress and health (Havelka, Lučanin, & Lučanin, 2009). Now that we understand how profoundly stressors can impact physical well-being, let’s explore some real-life situations that can trigger stress.

show what you know

Question 1

1. According to the ____________, the human body responds in a predictable way to stressors, following a specific pattern of physiological reactions.

general adaptation syndrome (GAS)

Question 2

2. As a police officer, Michelle has found herself in life-threatening situations. When faced with danger, Michelle’s body initially exhibits a fight-or-flight reaction, which is equivalent to the ____________ of the general adaptation syndrome.

  1. alarm stage

  2. exhaustion stage

  3. diseases of adaptation

  4. acculturative stress

a. alarm stage

Question 3

3. ____________ helps maintain balance in the body by overseeing the sympathetic nervous system, as well as the neuroendocrine and immune systems.

  1. The general adaptation syndrome

  2. The exhaustion stage

  3. The hypothalamic–pituitary–adrenal system

  4. Eustress

c. The hypothalamic–pituitary–adrenal system

Question 4

4. Infants of mothers subjected to extreme stressors may be born prematurely, have low birth weights, and exhibit behavioral difficulties. These outcomes result from increased levels of the stress hormone____________.

  1. H. pylori

  2. lymphocytes

  3. cortisol

  4. NK cells

c. cortisol

Question 5

5. Why are people under stress more likely to get sick?

When the body is expending its resources to deal with an ongoing stressor, the immune system is less powerful, and the work of the lymphocytes is compromised. During times of stress, people tend to sleep poorly and eat erratically, and may increase their drug and alcohol use, along with other poor behavioral choices. These tendencies can lead to health problems.