The struggle for independence in Latin America had lasted far longer and proved far more destructive than in North America. Decimated populations, diminished herds of livestock, flooded or closed silver mines, abandoned farms, shrinking international trade and investment capital, and empty national treasuries — these were the conditions that greeted Latin Americans upon independence. Furthermore, the four major administrative units (viceroyalties) of Spanish America ultimately dissolved into eighteen separate countries, and regional revolts wracked Brazil in the early decades of its independent life. A number of international wars in the post-independence century likewise shook these new nations. Peru and Bolivia briefly united and then broke apart in a bitter conflict (1836–1839); Mexico lost huge territories to the United States (1846–1848); and an alliance of Argentina, Brazil, and Uruguay went to war with Paraguay (1864–1870) in a conflict that devastated Paraguay’s small population.

Within these new countries, political life was turbulent and unstable. Conservatives favored centralized authority and sought to maintain the social status quo of the colonial era in alliance with the Catholic Church, which at independence owned perhaps half of all productive land. Their often-bitter opponents were liberals, who attacked the Church in the name of Enlightenment values, sought at least modest social reforms, and preferred federalism. In many countries, conflicts between these factions, often violent, enabled military strongmen known as caudillos (kaw-DEE-yos) to achieve power as defenders of order and property, although they too succeeded one another with great frequency. One of them, Antonio López de Santa Anna of Mexico, was president of his country at least nine separate times between 1833 and 1855. Constitutions too replaced one another with bewildering speed. Bolivia had ten constitutions during the nineteenth century, while Ecuador and Peru each had eight.

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Social life did not change fundamentally in the aftermath of independence. As in Europe and North America, women remained disenfranchised and wholly outside of formal political life. Slavery, it is true, was abolished in most of Latin America by midcentury, although it persisted in both Brazil and Cuba until the late 1880s. Most of the legal distinctions among various racial categories also disappeared, and all free people were considered, at least officially, equal citizens. Nevertheless, productive economic resources such as businesses, ranches, and plantations remained overwhelmingly in the hands of creole white men, who were culturally oriented toward Europe. The military provided an avenue of mobility for a few skilled and ambitious mestizo men, some of whom subsequently became caudillos. Other mixed-race men and women found a place in a small middle class as teachers, shopkeepers, or artisans. The vast majority — blacks, Indians, and many mixed-race people of both sexes — remained impoverished, working small subsistence farms or laboring in the mines or on the haciendas (ah-see-EHN-duhz) (plantations) of the well-to-do. Only rarely did the poor and dispossessed actively rebel against their social betters. One such case was the Caste War of Yucatán (1847–1901), a prolonged struggle of the Maya people of Mexico, aimed at cleansing their land of European and mestizo intruders.