Figure 19.3 
Conformational changes in citrate synthase on binding oxaloacetate. The small domain of each subunit of the homodimer is shown in yellow; the large domains are shown in blue. (Left) Open form of enzyme alone. (Right) Closed form of the liganded enzyme.
Conformational changes in citrate synthase on binding oxaloacetate. The small domain of each subunit of the homodimer is shown in yellow; the large domains are shown in blue. (Left) Open form of enzyme alone. (Right) Closed form of the liganded enzyme.