KEY TERMS

nucleoside

nucleotide

pyrimidine nucleotide

carbamoyl phosphate synthetase II (CPS II)

aspartate transcarbamoylase

5-phosphoribosyl-1-pyrophosphate (PRPP)

orotidylate

purine

inosinate

purinosomes

hypoxanthine-guanine phosphoribosyltransferase (HGPRT)

ribonucleotide reductase

thymidylate synthase

dihydrofolate reductase

severe combined immunodeficiency (SCID)

gout

Lesch–Nyhan syndrome

spina bifida