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Brief Contents

PART I The Molecular Design of Life
SECTION 1 Biochemistry Helps Us Understand Our World	1
Chapter 1 Biochemistry and the Unity of Life	3
Chapter 2 Water, Weak Bonds, and the Generation of Order Out of Chaos	17
SECTION 2 Protein Composition and Structure	35
Chapter 3 Amino Acids	37
Chapter 4 Protein Three-Dimensional Structure	47
Chapter 5 Techniques in Protein Biochemistry	69
SECTION 3 Basic Concepts and Kinetics of Enzymes	95
Chapter 6 Basic Concepts of Enzyme Action	97
Chapter 7 Kinetics and Regulation	111
Chapter 8 Mechanisms and Inhibitors	131
Chapter 9 Hemoglobin, an Allosteric Protein	149
SECTION 4 Carbohydrates and Lipids	165
Chapter 10 Carbohydrates	167
Chapter 11 Lipids	189
SECTION 5 Cell Membranes, Channels, Pumps, and Receptors	203
Chapter 12 Membrane Structure and Function	205
Chapter 13 Signal-Transduction Pathways	225
PART II Transducing and Storing Energy
SECTION 6 Basic Concepts and Design of Metabolism	245
Chapter 14 Digestion: Turning a Meal into Cellular Biochemicals	247
Chapter 15 Metabolism: Basic Concepts and Design	257
SECTION 7 Glycolysis and Gluconeogenesis	281
Chapter 16 Glycolysis	283
Chapter 17 Gluconeogenesis	313
SECTION 8 The Citric Acid Cycle	329
Chapter 18 Preparation for the Cycle	331
Chapter 19 Harvesting Electrons from the Cycle	343
SECTION 9 Oxidative Phosphorylation	361
Chapter 20 The Electron-Transport Chain	363
Chapter 21 The Proton-Motive Force	383
SECTION 10 The Light Reactions of Photosynthesis and the Calvin Cycle	405
Chapter 22 The Light Reactions	407
Chapter 23 The Calvin Cycle	427
SECTION 11 Glycogen Metabolism and the Pentose Phosphate Pathway	443
Chapter 24 Glycogen Degradation	445
Chapter 25 Glycogen Synthesis	459
Chapter 26 The Pentose Phosphate Pathway	473
SECTION 12 Fatty Acid and Lipid Metabolism	487
Chapter 27 Fatty Acid Degradation	489
Chapter 28 Fatty Acid Synthesis	507
Chapter 29 Lipid Synthesis: Storage Lipids, Phospholipids, and Cholesterol	523
SECTION 13 The Metabolism of Nitrogen- Containing Molecules	549
Chapter 30 Amino Acid Degradation and the Urea Cycle	551
Chapter 31 Amino Acid Synthesis	571
Chapter 32 Nucleotide Metabolism	585
PART III Synthesizing the Molecules of Life
SECTION 14 Nucleic Acid Structure and DNA Replication	605
Chapter 33 The Structure of Informational Macromolecules: DNA and RNA	607
Chapter 34 DNA Replication	627
Chapter 35 DNA Repair and Recombination	643
SECTION 15 RNA Synthesis, Processing, and Regulation	657
Chapter 36 RNA Synthesis and Regulation in Bacteria	659
Chapter 37 Gene Expression in Eukaryotes	675
Chapter 38 RNA Processing in Eukaryotes	691
SECTION 16 Protein Synthesis and Recombinant DNA Techniques	705
Chapter 39 The Genetic Code	707
Chapter 40 The Mechanism of Protein Synthesis	721
Chapter 41 Recombinant DNA Techniques	743

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