CHRONOLOGY

• – Christopher Columbus lands in the Caribbean and encounters the Tainos.
• – Columbian exchange begins.

• – Columbus makes second voyage to the New World.

• – Portugal and Spain sign the Treaty of Tordesillas.

• – John Cabot searches for the Northwest Passage.

• – Vasco Núñez de Balboa crosses the Isthmus of Panama.

• – Ferdinand Magellan sets out to sail around the world.