1519Hernán Cortés searches for wealth in Mexico.
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1520Mexica in Tenochtitlán revolt against Spaniards.
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1521 |
1532Francisco Pizarro begins conquest of Peru.
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1539Hernando de Soto explores southeastern North America.
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1540Francisco Vásquez de Coronado starts to explore Southwest and Great Plains.
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1542Juan Rodríguez Cabrillo explores California coast.
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1549Repartimiento reforms replace encomienda.
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1565St. Augustine, Florida, is settled.
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1598Juan de Oñate explores New Mexico.
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1599Acoma pueblo revolts against Oñate.
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