Although he is a decorated Air Force colonel, every three months he must endure what he calls the “stupid” test, an assessment of his memory. Roy and his wife Susan hope for a cure, or at least an intervention, that will slow progression of the disease. Four million Americans have Alzheimer's disease. Those who reach the age of 85 have a 50 percent chance of having the disease. One prominent researcher expresses hope for treatment. He sees light at the end of the tunnel, but obviously we are not yet through the tunnel. In 1907, Alois Alzheimer, a German neuropathologist, stated that the disorder was a disease and not just a function of aging. His autopsy of Frau Auguste D. revealed parts of brain cells twisted into weird tangles and deposits of sticky protein gunk now known as amyloid plaques. A vaccine that dissolves amyloid plaques is being tested on mice. Hopefully, test trials with humans will begin soon. Scientists are also studying how a variety of substances including inflammatory medications may impact Alzheimer's. Two drugs that temporarily relieve symptoms in some people are already marketed. Happier, healthier persons may decline more slowly. A variety of environmental factors may influence disease progression. Every time we stimulate our minds, we form new brain connections that will delay the onset of symptoms. Roy and Susan are volunteers in a study that examines how caregiver support impacts disease progression. For example, will Roy do better if Susan is doing well emotionally and physically? The couple intends to live fully as long as they can. There is much they still enjoy doing together.