For clarity, the pronouns this, that, which, and it should usually refer to specific antecedents rather than to whole ideas or sentences. When a pronoun’s reference is needlessly broad, you have two options for revision:
1. Replace the pronoun with a noun.
For clarity, the writer substituted a noun (chemotherapy) for the pronoun this, which referred broadly to the idea expressed in the preceding sentence.
2. Supply an antecedent to which the pronoun clearly refers.
Exercise: Pronoun reference 1
Exercise: Pronoun reference 2
Exercise: Pronoun reference 3
Exercise: Pronoun reference 4
antecedent The noun or pronoun to which a pronoun refers.