Table 29.3: Small nuclear ribonucleoprotein particles (snRNPs) in the splicing of mRNA precursors

snRNP

Size of snRNA (nucleotides)

Role

U1

165

Binds the 5′ splice site

U2

185

Binds the branch site and forms part of the catalytic center

U5

116

Binds the 5′ splice site and then the 3′ splice site

U4

145

Masks the catalytic activity of U6

U6

106

Catalyzes splicing