WEBVTT 1 00:00:04.000 --> 00:00:07.000 How does the signal jump across the synaptic gap? 2 00:00:07.000 --> 00:00:12.500 The process of synaptic transmission involves the release of neurotransmitter molecules 3 00:00:12.500 --> 00:00:17.000 that float across the synaptic gap and stimulate receptors in the next neuron. 4 00:00:17.000 --> 00:00:22.000 Let’s enlarge a synapse to take a closer look at this process. 5 00:00:22.000 --> 00:00:27.000 The axon terminal contains tiny sacs called synaptic vesicles. 6 00:00:27.000 --> 00:00:32.000 These sacs are filled with special chemicals known as neurotransmitters. 7 00:00:32.000 --> 00:00:37.000 When the neural impulse reaches the axon terminal, 8 00:00:37.000 --> 00:00:42.000 the vesicles open up and release their neurotransmitter molecules into the synaptic gap. 9 00:00:42.000 --> 00:00:45.000 The neurotransmitter molecules float across the gap, 10 00:00:45.000 --> 00:00:51.000 and find their way to special receptors on the surface of the other neuron's membrane. 11 00:00:51.000 --> 00:00:58.000 Here's a close up view of neurotransmitter molecules being released into the synaptic gap. 12 00:00:58.000 --> 00:01:02.000 Each neurotransmitter molecule is like a piece of a jigsaw puzzle. 13 00:01:02.000 --> 00:01:09.000 Each receptor or binding site will accept only a certain type of neurotransmitter. 14 00:01:09.000 --> 00:01:13.000 If the puzzle piece fits and the neurotransmitter binds to the receptor, 15 00:01:13.000 --> 00:01:22.000 a gate opens to allow ions to flow through a channel in the membrane into the interior of the post synaptic neuron.