Retrotransposition by a Ty element in yeast. The Ty element, within the host DNA, is transcribed to produce an mRNA, which is transported to the cell cytoplasm and translated to produce a polyprotein (pol) that is cleaved to generate a protease, reverse transcriptase, integrase, and Gag (a structural protein). Within the viruslike particle (VLP), reverse transcriptase converts the RNA to double-stranded DNA. The VLP is transported back into the nucleus, the Gag protein coat is shed, and the DNA transposon is integrated into a new target site in the host chromosome.