Recombination of the V and J gene segments of the human IgG kappa light chain. This process results in considerable antibody diversity. Shown at the top is the arrangement of IgG-coding sequences in a bone marrow stem cell. Recombination deletes the DNA between specific V and J segments. The RNA transcript is processed by RNA splicing; translation produces the light-chain polypeptide. The light chain can combine with any of several thousand possible heavy chains to produce an antibody molecule.