FIGURE 1 Gel revealing a viral-like ribozyme in human genomic RNA. Samples of the reaction mixture containing the transcript with the ribozyme sequence and flanking sequences were removed for analysis at different time intervals. Over time, the transcript was processed into shorter fragments corresponding to ribozyme-catalyzed strand cleavage at the junction between the 5′ flanking sequence and the boundary of the ribozyme sequence (shown in the representations to the right of the gel). M indicates a marker lane.