Examples of adenosine monophosphates. Adenosine 5′-monophosphate, with a phosphate group on C-5′, is the most common adenine-containing nucleotide and the one found in RNA. Adenosine 2′-monophosphate, adenosine 3′-monophosphate, and adenosine 2′,3′-cyclic monophosphate are formed during enzymatic or alkaline hydrolysis of RNA (see Figure 6-7). Adenosine 3′,5′-cyclic monophosphate (cAMP) is a signaling molecule that accumulates when the cell has a limited supply of nutrients.