KEY TERMS

enzyme

ligand

binding site

induced fit

cooperativity

dissociation constant (Kd)

cofactor

coenzyme

prosthetic group

holoenzyme

apoenzyme (apoprotein)

substrate

active site

biochemical standard free-energy change (ΔG′°)

transition state

maximum velocity (Vmax)

steady-state kinetics

Michaelis-Menten equation

Michaelis constant (Km)

turnover number

helicase

regulatory enzyme

allosteric enzyme (allosteric protein)

allosteric modulator

homotropic

heterotropic

autoinhibition

protein kinase

protein phosphatase