I

FOUNDATIONS

1

Evolution, Science, and Molecular Biology

2

DNA: The Repository of Biological Information

3

Chemical Basis of Information Molecules

4

Protein Structure

5

Protein Function

II

NUCLEIC ACID STRUCTURE AND METHODS

6

DNA and RNA Structure

7

Studying Genes

8

Genomes, Transcriptomes, and Proteomes

9

Topology: Functional Deformations of DNA

10

Nucleosomes, Chromatin, and Chromosome Structure

III

INFORMATION TRANSFER

11

DNA Replication

12

DNA Mutation and Repair

13

Recombinational DNA Repair and Homologous Recombination

14

Site-Specific Recombination and Transposition

15

Transcription: DNA-Dependent Synthesis of RNA

16

RNA Processing

17

The Genetic Code

18

Protein Synthesis

IV

REGULATION

19

Regulating the Flow of Information

20

The Regulation of Gene Expression in Bacteria

21

The Transcriptional Regulation of Gene Expression in Eukaryotes

22

The Posttranscriptional Regulation of Gene Expression in Eukaryotes

Model Organisms Appendix

Glossary

Solutions to Problems

Index