General

Kornberg, A. 1989. For the Love of Enzymes: The Odyssey of a Biochemist. Cambridge, MA: Harvard University Press.

Kornberg, A., and T. Baker. 1991. DNA Replication, 2nd ed. New York: W.H. Freeman and Company.

Lehman, I.R. 2006. Wanderings of a DNA enzymologist: From DNA polymerase to viral latency. Annu. Rev. Biochem. 75:1–17.

DNA Transactions during Replication

Cairns, J. 1963. The chromosome of Escherichia coli. Cold Spring Harb. Symp. Quant. Biol. 28:43–46.

Meselson, M., and F.W. Stahl. 1958. The replication of DNA in Escherichia coli. Proc. Natl. Acad. Sci. USA 44:671–682. A classic study, very well written, with elegant experimental rationale and results.

Okazaki R., T. Okazaki, K. Sakabe, K. Sugimoto, R. Kainuma, A. Sugino, and N. Iwatsuki. 1968. In vivo mechanism of DNA chain growth. Cold Spring Harb. Symp. Quant. Biol. 3:129–143.

The Chemistry of DNA Polymerases

Doublie, S., S. Tabor, A.M. Long, C.C. Richardson, and T. Ellenberger. 1998. Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 Å resolution. Nature 391:251–258. Description of the first time that a DNA polymerase was crystallized with a primed template and bound dNTP.

Joyce, C.M., and S.J. Benkovic. 2004. DNA polymerase fidelity: Kinetics, structure, and checkpoints. Biochemistry 43:14,317–14,324.

Steitz, T.A. 1999. DNA polymerases: Structural diversity and common mechanisms. J. Biol. Chem. 274:17,395–17,398. Overview that compares and contrasts DNA polymerase structures in the different polymerase families.

Mechanics of the DNA Replication Fork

Benkovic, S.J., A.M. Valentine, and F. Salinas. 2001. Replisome-mediated DNA replication. Annu. Rev. Biochem. 70:181–208.

McHenry, C.S. 2003. Chromosomal replicases as asymmetric dimers: Studies of subunit arrangement and functional consequences. Mol. Microbiol. 49:1157–1165.

Mok, M., and K.J. Marians. 1987. Formation of rolling-circle molecules during phi X174 complementary strand DNA replication. J. Biol. Chem. 262:2304–2309.

Stillman, B. 2008. DNA polymerases at the replication fork in eukaryotes. Mol. Cell 30:259–260.

Yao, N.Y., and M. O’Donnell. 2008. Replisome dynamics and use of DNA trombone loops to bypass replication blocks. Mol. Biosyst. 4:1075–1084.

Initiation of DNA Replication

Boos, D., J. Frigola, and J.F. Diffley. 2012. Activation of the replicative DNA helicase: Breaking up is hard to do. Curr. Opin. Cell. Biol. 24:423–430.

Li, H., and B. Stillman. 2012. The origin recognition complex: A biochemical and structural view. Subcell. Biochem. 62:37–58

O’Donnell, M., L. Langston, and B. Stillman. 2013. Principles and concepts of DNA replication in bacteria, archaea, and eukarya. Cold Spring Harb. Perspect. Biol., doi:10.1101/cshperspect.a010108. http://cshperspectives.cshlp.org/content/5/7/a010108.full.pdf+html.

Tsakraklides, V., and S.P. Bell. 2010. Dynamics of pre-replicative complex assembly. J. Biol. Chem. 285:9437–9443.

Termination of DNA Replication

Armanios, M., and E.H. Blackburn. 2012. The telomere syndromes. Nat. Rev. Genet. 13:693–704.

Greider, C. 2009. Telomerase Discovery: The Excitement of Putting Together Pieces of the Puzzle. Nobel lecture. The Nobel Prize in Physiology or Medicine 2009: Elizabeth H. Blackburn, Carol W. Greider, Jack W. Szostak. Video. www.nobelprize.org/nobel_prizes/medicine/laureates/2009/greider-lecture.html.

Nandakumar, J., and T.R. Cech. 2013. Finding the end: Recruitment of telomerase to the telomere. Nat. Rev. 14:69–82.

Palm, W., and T. de Lange. 2008. How shelterin protects mammalian telomeres. Annu. Rev. Genet. 42:301–334.

Skloot, R. 2010. The Immortal Life of Henrietta Lacks. New York: Crown Publishers.

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