KEY TERMS

DNA replication

semiconservative

autoradiograph

origin of replication

replication fork

DNA polymerase

semidiscontinuous

leading strand

lagging strand

Okazaki fragment

template strand

primer strand

primer terminus

primed template

insertion site

postinsertion site

DNA nuclease

proofreading

nick translation

distributive synthesis

processive synthesis

Pol III holoenzyme

β sliding clamp

clamp loader

AAA+ proteins

DNA helicase

topoisomerase

primase

RNaseH

DNA ligase

single-stranded DNA–binding protein (SSB)

replisome

trombone model

MCM complex

CMG complex

replisome progression complex (RPC)

replicon

initiator protein

origin recognition complex (ORC)

prereplication complex (preRC)

Ter site

end replication problem

telomere

telomerase