Conclusion
Charles V’s decision to divide his empire reflected the tensions pulling Europe in different directions. Even as Charles’s kingdom of Spain joined Portugal as a global power with new conquests overseas, Luther, Calvin, and a host of others sought converts to competing branches of Protestantism within the Holy Roman Empire. The reformers disagreed on many points of doctrine and church organization, but they all broke definitively from the Roman Catholic church. The pieces were never put together again. Portugal and Spain, the leaders in global exploration and conquest, remained resolutely Catholic, but as ruler of the Holy Roman Empire, where the Reformation began, Charles could not stifle the growing religious ferment. In the decades to come, Protestantism would spread, religious conflict would turn even more deadly, and emerging Protestant powers would begin to contest the global reach of Spain and Portugal.