FIGURE 16-2 Early-Onset Schizophrenia Comparison of three-dimensional maps derived from MRI scans reveals that, compared with healthy teenagers aged 13 to 18 (left), patients with childhood-onset schizophrenia (right) have widespread loss of gray matter across the cerebral hemispheres.

Courtesy of Paul Thompson and Arthur W. Toga, Laboratory of Neuro Imaging, Keck School of Medicine of USC and Judith L. Rapoport, National Institute of Mental Health.