| Category | Number of genes in: | ||
|---|---|---|---|
| E. coli | H. influenzae | M. genitalium | |
| Total protei | 4,288 | 1,727 | 482 |
| Biosynthesis of amino acids | 131 | 68 | 1 |
| Biosynthesis of cofactors | 103 | 54 | 5 |
| Biosynthesis of nucleotides | 58 | 53 | 19 |
| Cell envelope proteins | 237 | 84 | 17 |
| Energy metabolism | 243 | 112 | 31 |
| Intermediary metabolism | 188 | 30 | 6 |
| Lipid metabolism | 48 | 25 | 6 |
| DNA replication, recombination, and repair | 115 | 87 | 32 |
| Protein folding | 9 | 6 | 7 |
| Regulatory proteins | 178 | 64 | 7 |
| Transcription | 55 | 27 | 12 |
| Translation | 182 | 141 | 101 |
| Uptake of molecules from the environment | 427 | 123 | 34 |