Many signaling pathways and plant responses are shared between general and specific immunity, although in the latter these responses are accelerated and amplified. Furthermore, specific immunity usually leads to a form of programmed cell death called the hypersensitive response. When this occurs, plant cells at and near the site of pathogen infection die, forming a necrotic lesion. This cell death deprives the pathogen of nutrients and prevents the spread of the infection. The rest of the plant remains pathogen-free.