Chapter 1. Parabiotic Mice Simulation

Parabiotic Mice Simulation

Question 1.1

You inject a mouse of unknown genotype with leptin and obtain data shown in the graph below.

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Correct. See Key Concept 50.4 Nutrient Availability Is Controlled and Regulated
Incorrect. See Key Concept 50.4 Nutrient Availability Is Controlled and Regulated

Question 1.2

You surgically join two mice to form a parabiotic pair. What is the most likely genotype of the mouse (one member of the parabiotic pair) described by the graph below?

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Correct. See Key Concept 50.4 Nutrient Availability Is Controlled and Regulated
Incorrect. See Key Concept 50.4 Nutrient Availability Is Controlled and Regulated

Question 1.3

How are the mice from the two graphs below similar?

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Correct. See Key Concept 50.4 Nutrient Availability Is Controlled and Regulated
Incorrect. See Key Concept 50.4 Nutrient Availability Is Controlled and Regulated

Question 1.4

What would you observe in the following pairs of parabiotic mice?

Pair 1: WT + ob/ob
Pair 2: WT + db/db

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Correct. See Key Concept 50.4 Nutrient Availability Is Controlled and Regulated
Incorrect. See Key Concept 50.4 Nutrient Availability Is Controlled and Regulated

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