Microtubule Structure and Organization

Badano, J. L., T. M. Teslovich, and N. Katsanis. 2005. The centrosome in human genetic disease. Nat. Rev. Mol. Cell Biol. 6:194–205.

Doxsey, S. 2001. Re-evaluating centrosome function. Nat. Rev. Mol. Cell Biol. 2:688–698.

Dutcher, S. K. 2001. The tubulin fraternity: alpha to eta. Curr. Opin. Cell Biol. 13:49–54.

Nogales, E., and H-W Wang. 2006. Structural intermediates in microtubule assembly and disassembly: how and why? Curr. Opin. Cell Biol. 18:179–184.

Microtubule Dynamics

Akhmanova, A., and M. O. Steinmetz. 2010. Microtubule +TIPs at a glance. J. Cell Sci. 123:3414–3418.

Brouhard, G. Y., and L. M. Rice. 2014. The contribution of αβ-tubulin curvature to microtubule dynamics. J. Cell Biol. 207:323–334.

Cassimeris, L. 2002. The oncoprotein 18/stathmin family of microtubule destabilizers. Curr. Opin. Cell Biol. 14:18–24.

Desai, A., and T. J. Mitchison. 1997. Microtubule polymerization dynamics. Annu. Rev. Cell Dev. Bi. 13:83–117.

Galjart, N. 2010. Plus-end-tracking proteins and their interactions at microtubule ends. Curr. Biol. 20:R528–R537.

Hammond, J. W., D. Cai, and K. J. Verhey. 2008. Tubulin modifications and their cellular functions. Curr. Opin. Cell Biol. 20:71–76.

Howard, J., and A. A. Hyman. 2003. Dynamics and mechanics of the microtubule plus end. Nature 422:753–758.

Wloga, D., and J. Gaertig. 2010. Post-translational modifications of microtubules. J. Cell Sci. 123:3447–3455.

Zheng, Y., and P. A. Iglesias. 2013. Nucleating new branches from old. Cell 152:669–670.

Kinesins and Dyneins: Microtubule-Based Motor Proteins

Web site: Kinesin Home Page, https://labs.cellbio.duke.edu/kinesin/

Allan, V. 2014. One, two, three, cytoplasmic dynein is go! Nature 345:271–272.

Bhabha, G., et al. 2014. Allosteric communication in the dynein motor domain. Cell 159:857–868.

Burgess, S. A., et al. 2003. Dynein structure and power stroke. Nature 421:715–718.

Carter, A. P., et al. 2011. The crystal structure of dynein. Science 331:1159–1165.

Cho, C., and R. D. Vale. 2012. The mechanism of dynein motility: insight from crystal structures of the motor domain. Biochim. Biophys. Acta 1823:182–191.

Dell, K. R. 2003. Dynactin polices two-way organelle traffic. J. Cell Biol. 160:291–293.

Dujardin, D. L., and R. B. Vallee. 2002. Dynein at the cortex. Curr. Opin. Cell Biol. 14:44–49.

Endow, S. A., F. J Kull, and H. Liu. 2010. Kinesins at a glance. J. Cell Sci. 123:3420–3424.

Goldstein, L. S. 2001. Kinesin molecular motors: transport pathways, receptors, and human disease. P. Natl. Acad. Sci. USA 98:6999–7003.

Hirokawa, N., et al. 2009. Kinesin superfamily motor proteins and intracellular transport. Nat. Rev. Mol. Cell Biol. 10:682–696.

Hirokawa, N., and R. Takemure. 2003. Biochemical and molecular characterization of diseases linked to motor proteins. Trends Cell Biol. 28:558–565.

Kardon, J. R., and R. D. Vale. 2009. Regulators of the cytoplasmic dynein motor. Nat. Rev. Mol. Cell Biol. 10:854–865.

Lawrence, C. J., et al. 2004. A standardized kinesin nomenclature. J. Cell Biol. 167:19–22.

McKenney, R. J., et al. 2010. LIS1 and NudE induce a persistent dynein force-producing state. Cell 141:304–314.

McKenney, R. J., et al. 2014. Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes. Nature 345:337–341.

Roberts, A. J., et al. 2013. Functions and mechanics of dynein motor proteins. Nat. Rev. Mol. Cell Biol. 14:713–726.

Schroer, T. A. 2004. Dynactin. Annu. Rev. Cell Dev. Biol. 20:759–779.

Trokter, M. and T. Surrey. 2012. Lis1 clamps dynein to the microtubule. Cell 150:877–879.

Vale, R. D. 2003. The molecular motor toolbox for intracellular transport. Cell 112:467–480.

Vale, R. D., and R. A. Milligan. 2000. The way things move: looking under the hood of molecular motor proteins. Science 288:88–95.

Verhey, K. J., and J. W. Hammond. 2009. Traffic control: regulation of kinesin motors. Nat. Rev. Mol. Cell Biol. 10:765–777.

Wordeman, L. 2005. Microtubule-depolymerizing kinesins. Curr. Opin. Cell Biol. 17:82–88.

Yildiz, A., et al. 2004. Kinesin walks hand-over-hand. Science 303:676–678.

Cilia and Flagella: Microtubule-Based Surface Structures

Gerdes, J. M., E. E. Davis, and N. Katsanis. 2009. The vertebrate primary cilium in development, homeostasis, and disease. Cell 137:32–45.

Ishikawa, H., and W. F. Marshall. 2011. Ciliogenesis: building the cell’s antenna. Nat. Rev. Mol. Cell Biol. 12:222–234.

Jin, H., et al. 2010. The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia. Cell 141:1208–1218.

Rosenbaum, J. L., and G. B. Witman. 2002. Intraflagellar transport. Nat. Rev. Mol. Cell Biol. 3:813–825.

Singla, V., and J. F. Reiter. 2006. The primary cilium as the cells’ antenna: signaling at a sensory organelle. Science 313:629–633.

Mitosis

Web site: http://labs.bio.unc.edu/Salmon/mitosis/mitosis.html

Alushin, G. M., et al. 2010. The Ndc80 kinetochore complex forms oligomeric arrays along microtubules. Nature 467:805–810.

Cheeseman, I. M., and A. Desai. 2008. Molecular architecture of the kinetochore-microtubule interface. Nat. Rev. Mol. Cell Biol. 9:33–46.

Cleveland, D. W., Y. Mao, and K. F. Sullivan. 2003. Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling. Cell 112:407–421.

Foley, E. A., and T. M. Kapoor. 2013. Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore. Nat. Rev. Cell Mol. Biol. 14:25–37.

Gadde, S., and R. Heald. 2004. Mechanisms and molecules of the mitotic spindle. Curr. Biol. 14:R797–R805.

Goshima, G., et al. 2009. Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle. J. Cell Biol. 181:421–429.

Heald, R., et al. 1997. Spindle assembly in Xenopus egg extracts: respective roles of centrosomes and microtubule self-organization. J. Cell Biol. 138:615–628.

Jürgens, G. 2005. Cytokinesis in higher plants. Annu. Rev. Plant Biol. 56:281–299.

Kim, Y., et al. 2010. Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-E. Cell 142:444–455.

Kinoshita, K., B. Habermann, and A. A. Hyman. 2002. XMAP215: a key component of the dynamic microtubule cytoskeleton. Trends Cell Biol. 12:267–273.

Lampert, F., and S. Westermann. 2011. A blueprint for kinetochores—new insights into the molecular mechanics of cell division. Nat. Rev. Mol. Cell Biol. 12:407–412.

Liu, D., et al. 2009. Sensing chromosome bi-orientation by spatial separation of Aurora B kinase from kinetochore substrates. Science 323:1350–1353.

London, N., and S. Biggins. 2014. Signalling dynamics in the spindle checkpoint response. Nat. Rev. Mol. Cell Biol. 15:735–747.

Mitchison, T. J., and E. D. Salmon. 2001. Mitosis: a history of division. Nat. Cell Biol. 3:E17–E21.

Rogers, G. C., et al. 2004. Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase. Nature 427:364–370.

Ruchaud, S., M. Carmena, and W. C. Earnshaw. 2007. Chromosomal passengers: conducting cell division. Nat. Rev. Mol. Cell Biol. 8:798–812.

Santaguida, S., and A. Musacchio. 2009. The life and miracle of kinetochores. EMBO J. 28:2511–2531.

Wang, H., I. Brust-Mascher, and J. M. Scholey. 2014. Sliding filaments and mitotic spindle organization. Nat. Cell Biol. 16:737–739.

Wittmann, T., A. Hyman, and A. Desai. 2001. The spindle: a dynamic assembly of microtubules and motors. Nat. Cell Biol. 3:E28–E34.

Intermediate Filaments

Burke, B., and C. L. Stewart. 2013. The nuclear lamins: flexibility in function. Nat. Rev. Mol. Cell Biol. 14:13–23.

Colakoglu, G., and A. Brown. 2009. Intermediate filaments exchange subunits along their length and elongate by end-to-end annealing. J. Cell Biol. 185:769–777.

Goldman, R. D., et al. 2002. Nuclear lamins: building blocks of nuclear architecture. Genes Dev. 16:533–547.

Herrmann, H., and U. Aebi. 2000. Intermediate filaments and their associates: multi-talented structural elements specifying cytoarchitecture and cytodynamics. Curr. Opin. Cell Biol. 12:79–90.

Isermann, P., and J. Lammerding. 2013. Nuclear mechanics and mechanotransduction in health and disease. Curr. Biol. 23:R1113–R1121.

Luxton, G. W. G., and D. A. Starr. 2014. KASHing up with the nucleus: novel functional roles of KASH proteins at the cytoplasmic surface of the nucleus. Curr. Opin. Cell Biol. 28:69–75.

Mattout, A., et al. 2006. Nuclear lamins, disease and aging. Curr. Opin. Cell Biol. 18:335–341.

Worman, H. J. 2012. Nuclear lamins and laminopathies. J. Pathol. 226:316–325.

Coordination and Cooperation Between Cytoskeletal Elements

Chang, L., and R. D. Goldman. 2004. Intermediate filaments mediate cytoskeletal crosstalk. Nat. Rev. Mol. Cell Biol. 5:601–613.

Etienne-Manneville, S., et al. 2005. Cdc42 and Par6-PKCζ regulate the spatially localized association of Dlg1 and APC to control cell polarization. J. Cell Biol. 170:895–901.

Kodama, A., T. Lechler, and E. Fuchs. 2004. Coordinating cytoskeletal tracks to polarize cellular movements. J. Cell Biol. 167:203–207.

Schaefer, A. W., et al. 2008. Coordination of actin filament and microtubule dynamics during neurite outgrowth. Dev. Cell 15:146–162.

Wu, X., X. Xiang, and J. A. Hammer III. 2006. Motor proteins at the microtubule plus-end. Trends Cell Biol. 16:135–143.