FileTitleManuscript Id
Chapter Introductionlodish8e_ch19_1.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_1_dlap.xml56f563fc757a2e8473000002
19.1 Overview of the Cell Cycle and Its Control lodish8e_ch19_2.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_2_dlap.xml56f563fc757a2e8473000002
The Cell Cycle Is an Ordered Series of Events Leading to Cell Replication lodish8e_ch19_3.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_3_dlap.xml56f563fc757a2e8473000002
Cyclin-Dependent Kinases Control the Eukaryotic Cell Cycle lodish8e_ch19_4.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_4_dlap.xml56f563fc757a2e8473000002
Several Key Principles Govern the Cell Cycle lodish8e_ch19_5.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_5_dlap.xml56f563fc757a2e8473000002
Key Concepts of Section 19.1lodish8e_ch19_6.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_6_dlap.xml56f563fc757a2e8473000002
19.2 Model Organisms and Methods of Studying the Cell Cycle lodish8e_ch19_7.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_7_dlap.xml56f563fc757a2e8473000002
Budding and Fission Yeasts Are Powerful Systems for Genetic Analysis of the Cell Cycle lodish8e_ch19_8.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_8_dlap.xml56f563fc757a2e8473000002
Frog Oocytes and Early Embryos Facilitate Biochemical Characterization of the Cell Cycle Machinery lodish8e_ch19_9.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_9_dlap.xml56f563fc757a2e8473000002
Fruit Flies Reveal the Interplay Between Development and the Cell Cycle lodish8e_ch19_10.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_10_dlap.xml56f563fc757a2e8473000002
The Study of Tissue Culture Cells Uncovers Cell Cycle Regulation in Mammals lodish8e_ch19_11.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_11_dlap.xml56f563fc757a2e8473000002
Researchers Use Multiple Tools to Study the Cell Cycle lodish8e_ch19_12.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_12_dlap.xml56f563fc757a2e8473000002
Key Concepts of Section 19.2lodish8e_ch19_13.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_13_dlap.xml56f563fc757a2e8473000002
19.3 Regulation of CDK Activity lodish8e_ch19_14.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_14_dlap.xml56f563fc757a2e8473000002
Cyclin-Dependent Kinases Are Small Protein Kinases That Require a Regulatory Cyclin Subunit for Their Activity lodish8e_ch19_15.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_15_dlap.xml56f563fc757a2e8473000002
Cyclins Determine the Activity of CDKs lodish8e_ch19_16.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_16_dlap.xml56f563fc757a2e8473000002
Cyclin Levels Are Primarily Regulated by Protein Degradation lodish8e_ch19_17.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_17_dlap.xml56f563fc757a2e8473000002
CDKs Are Regulated by Activating and Inhibitory Phosphorylation lodish8e_ch19_18.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_18_dlap.xml56f563fc757a2e8473000002
CDK Inhibitors Control Cyclin-CDK Activity lodish8e_ch19_19.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_19_dlap.xml56f563fc757a2e8473000002
Genetically Engineered CDKs Led to the Discovery of CDK Functions lodish8e_ch19_20.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_20_dlap.xml56f563fc757a2e8473000002
Key Concepts of Section 19.3lodish8e_ch19_21.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_21_dlap.xml56f563fc757a2e8473000002
19.4 Commitment to the Cell Cycle and DNA Replication lodish8e_ch19_22.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_22_dlap.xml56f563fc757a2e8473000002
Cells Are Irreversibly Committed to Division at a Cell Cycle Point Called START or the Restriction Point lodish8e_ch19_23.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_23_dlap.xml56f563fc757a2e8473000002
The E2F Transcription Factor and Its Regulator Rb Control the G1–S Phase Transition in Metazoans lodish8e_ch19_24.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_24_dlap.xml56f563fc757a2e8473000002
Extracellular Signals Govern Cell Cycle Entry lodish8e_ch19_25.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_25_dlap.xml56f563fc757a2e8473000002
Degradation of an S Phase CDK Inhibitor Triggers DNA Replication lodish8e_ch19_26.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_26_dlap.xml56f563fc757a2e8473000002
Replication at Each Origin Is Initiated Once and Only Once During the Cell Cycle lodish8e_ch19_27.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_27_dlap.xml56f563fc757a2e8473000002
Duplicated DNA Strands Become Linked During Replication lodish8e_ch19_28.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_28_dlap.xml56f563fc757a2e8473000002
Key Concepts of Section 19.4lodish8e_ch19_29.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_29_dlap.xml56f563fc757a2e8473000002
19.5 Entry into Mitosis lodish8e_ch19_30.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_30_dlap.xml56f563fc757a2e8473000002
Precipitous Activation of Mitotic CDKs Initiates Mitosis lodish8e_ch19_31.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_31_dlap.xml56f563fc757a2e8473000002
Mitotic CDKs Promote Nuclear Envelope Breakdown lodish8e_ch19_32.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_32_dlap.xml56f563fc757a2e8473000002
Mitotic CDKs Promote Mitotic Spindle Formation lodish8e_ch19_33.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_33_dlap.xml56f563fc757a2e8473000002
Chromosome Condensation Facilitates Chromosome Segregation lodish8e_ch19_34.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_34_dlap.xml56f563fc757a2e8473000002
Key Concepts of Section 19.5lodish8e_ch19_35.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_35_dlap.xml56f563fc757a2e8473000002
19.6 Completion of Mitosis: Chromosome Segregation and Exit from Mitosis lodish8e_ch19_36.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_36_dlap.xml56f563fc757a2e8473000002
Separase-Mediated Cleavage of Cohesins Initiates Chromosome Segregation lodish8e_ch19_37.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_37_dlap.xml56f563fc757a2e8473000002
APC/C Activates Separase Through Securin Ubiquitinylation lodish8e_ch19_38.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_38_dlap.xml56f563fc757a2e8473000002
Mitotic CDK Inactivation Triggers Exit from Mitosis lodish8e_ch19_39.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_39_dlap.xml56f563fc757a2e8473000002
Cytokinesis Creates Two Daughter Cells lodish8e_ch19_40.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_40_dlap.xml56f563fc757a2e8473000002
Key Concepts of Section 19.6lodish8e_ch19_41.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_41_dlap.xml56f563fc757a2e8473000002
19.7 Surveillance Mechanisms in Cell Cycle Regulation lodish8e_ch19_42.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_42_dlap.xml56f563fc757a2e8473000002
Checkpoint Pathways Establish Dependencies and Prevent Errors in the Cell Cycle lodish8e_ch19_43.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_43_dlap.xml56f563fc757a2e8473000002
The Growth Checkpoint Pathway Ensures That Cells Enter the Cell Cycle Only After Sufficient Macromolecule Biosynthesis lodish8e_ch19_44.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_44_dlap.xml56f563fc757a2e8473000002
The DNA Damage Response System Halts Cell Cycle Progression When DNA Is Compromised lodish8e_ch19_45.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_45_dlap.xml56f563fc757a2e8473000002
The Spindle Assembly Checkpoint Pathway Prevents Chromosome Segregation Until Chromosomes Are Accurately Attached to the Mitotic Spindle lodish8e_ch19_46.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_46_dlap.xml56f563fc757a2e8473000002
The Spindle Position Checkpoint Pathway Ensures That the Nucleus Is Accurately Partitioned Between Two Daughter Cells lodish8e_ch19_47.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_47_dlap.xml56f563fc757a2e8473000002
Key Concepts of Section 19.7lodish8e_ch19_48.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_48_dlap.xml56f563fc757a2e8473000002
19.8 Meiosis: A Special Type of Cell Division lodish8e_ch19_49.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_49_dlap.xml56f563fc757a2e8473000002
Extracellular and Intracellular Cues Regulate Germ Cell Formation lodish8e_ch19_50.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_50_dlap.xml56f563fc757a2e8473000002
Several Key Features Distinguish Meiosis from Mitosis lodish8e_ch19_51.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_51_dlap.xml56f563fc757a2e8473000002
Recombination and a Meiosis-Specific Cohesin Subunit Are Necessary for the Specialized Chromosome Segregation in Meiosis I lodish8e_ch19_52.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_52_dlap.xml56f563fc757a2e8473000002
Co-orienting Sister Kinetochores Is Critical for Meiosis I Chromosome Segregation lodish8e_ch19_53.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_53_dlap.xml56f563fc757a2e8473000002
DNA Replication Is Inhibited Between the Two Meiotic Divisions lodish8e_ch19_54.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_54_dlap.xml56f563fc757a2e8473000002
Key Concepts of Section 19.8lodish8e_ch19_55.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_55_dlap.xml56f563fc757a2e8473000002
Key Terms lodish8e_ch19_56.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_56_dlap.xml56f563fc757a2e8473000002
Review the Concepts lodish8e_ch19_57.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_57_dlap.xml56f563fc757a2e8473000002
References lodish8e_ch19_58.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_58_dlap.xml56f563fc757a2e8473000002
Perspectives for the Future: Cell Cycle Checkpoints and Regulation lodish8e_ch19_59.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_59_dlap.xml56f563fc757a2e8473000002
Classic Experiment 19-1: How Cyclins Were Discoveredlodish8e_ch19_60.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_60_dlap.xml56f563fc757a2e8473000002
Classic Experiment 19-2: Synthesis and Degradation of Mitotic Cyclin Are Required for Progression through Mitosislodish8e_ch19_61.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_61_dlap.xml56f563fc757a2e8473000002
Classic Experiment 19-3: The Formulation of the Checkpoint Conceptlodish8e_ch19_62.html56f563fc757a2e8473000002
DLAP questionslodish8e_ch19_62_dlap.xml56f563fc757a2e8473000002