In the late Middle Ages, the Italian city-states of Venice and Genoa controlled the European luxury trade with the East. In 1304, Venice established formal relations with the sultan of Mamluk Egypt, opening operations in Cairo, the gateway to Asian trade. Venetian merchants specialized in luxury goods which they obtained from middlemen in the eastern Mediterranean and Asia Minor.2

Venice’s ancient rival was Genoa. In the wake of the Crusades, Genoa dominated the northern route to Asia through the Black Sea. Expansion in the thirteenth and fourteenth centuries took the Genoese as far as Persia and the Far East. In 1291, they sponsored an expedition into the Atlantic in search of India. The ships were lost, and their exact destination and motivations remain unknown. This voyage reveals the long roots of Genoese interest in Atlantic exploration.

In the fifteenth century, with Venice claiming victory in the spice trade, the Genoese shifted focus from trade to finance and from the Black Sea to the western Mediterranean. When Spanish and Portuguese voyages began to explore the western Atlantic (see pages 419–421), Genoese merchants, navigators, and financiers provided their skills to the Iberian monarchs, whose own subjects had much less commercial experience. Genoese merchants would eventually help finance Spanish colonization of the New World.

A major element of Italian trade was slavery. Merchants purchased slaves, many of whom were fellow Christians, in the Balkans. The men were sold to Egypt for the sultan’s army or sent to work as agricultural laborers in the Mediterranean. Young girls, who constituted the majority of the trade, were sold in western Mediterranean ports as servants or concubines. After the loss of the Black Sea — and thus the source of slaves — to the Ottomans, the Genoese sought new supplies of slaves in the West, taking the Guanches (indigenous peoples from the Canary Islands), Muslim prisoners and Jewish refugees from Spain, and by the early 1500s both black and Berber Africans. With the growth of Spanish colonies in the New World, Genoese and Venetian merchants would become important players in the Atlantic slave trade.

Italian experience in colonial administration, slaving, and international trade served as a model for the Iberian states as they pushed European expansion to new heights. Mariners, merchants, and financiers from Venice and Genoa — most notably Christopher Columbus — played a crucial role in bringing the fruits of this experience to the Iberian Peninsula and to the New World.