The Wonderful Effects of the New Inoculation! The talented caricaturist James Gillray satirized widespread anxieties about the smallpox vaccination in this lively image. The discoveries of Edward Jenner a few years prior to Gillray’s caricature had led to the adoption of a safer vaccine derived from cowpox. The artist mocks this breakthrough by showing cows bursting from the boils supposedly brought on by the vaccine.
(Private Collection/Bridgeman Images)