Once a complete set of chromosomes arrives at a pole, the chromosomes have entered the area that will form the cytosol of a new daughter cell. This event marks the beginning of telophase, during which the cell prepares for its division into two new cells (see Fig. 11.5). The microtubules of the mitotic spindle break down and disappear, while a nuclear envelope reforms around each set of chromosomes, creating two new nuclei. As the nuclei become increasingly distinct in the cell, the chromosomes contained within them decondense, becoming less visible in the microscope. This stage marks the end of mitosis.