Structure Genes Encoded Transposition Examples
Class I (retrotransposon) Long terminal direct repeats; short flanking direct repeats at target site Reverse-transcriptase gene (and sometimes others) By RNA intermediate Ty (yeast) copia (Drosophila) Alu (human)
Class II Short terminal inverted repeats; short flanking direct repeats at target site Transposase gene (and sometimes others) Through DNA (replicative or nonreplicative) IS1 (E. coli) Tn3 (E. coli) Ac, Ds (maize) P elements (Drosophila)
Table 18.4: Characteristics of two major classes of transposable genetic elements