Repair System Type of Damage Repaired
Mismatch Replication errors, including mispaired bases and strand slippage
Direct Pyrimidine dimers; other specific types of alterations
Base excision Abnormal bases, modified bases, and pyrimidine dimers
Nucleotide excision DNA damage that distorts the double helix, including abnormal bases, modified bases, and pyrimidine dimers
Homologous recombination Double-strand breaks
Nonhomologous end joining Double-strand breaks
Table 18.5: Summary of common DNA repair mechanisms