Figure 19.21: A candidate for the cystic fibrosis gene is expressed in pancreatic, respiratory, and sweat-gland tissues—tissues that are affected by the disease. Shown is a Northern blot of mRNA produced by the candidate gene in different tissues. These data provided evidence that the candidate gene is in fact the gene that causes cystic fibrosis.
[From J.R. Riordan et al., Science 245:1066-1073, 1989. Reprinted with permission from AAAS.]