Figure 19.37: Transfer of siRNAs for the ApoB protein into cynomolgus monkeys significantly lowered blood-cholesterol levels. (a) Cynomolgus monkey. (b) Different groups of monkeys were given saline (control), a 1-mg/kg dose, or a 2.5-mg/kg dose of siRNAs.
[Part a: Tony Camacho/Science Source. Part b: After T. S. Zimmerman, Nature, 441:112, 2006, Figure 3b.]