Stage Major Features
Meiosis I
Prophase I Chromosomes condense, homologous chromosomes synapse, crossing over takes place, the nuclear envelope breaks down, and the mitotic spindle forms.
Metaphase I Homologous pairs of chromosomes line up on the metaphase plate.
Anaphase I The two chromosomes (each with two chromatids) of each homologous pair separate and move toward opposite poles.
Telophase I Chromosomes arrive at the spindle poles.
Cytokinesis The cytoplasm divides to produce two cells, each having half the original number of chromosomes.
Interkinesis In some types of cells, the spindle breaks down, chromosomes relax, and a nuclear envelope re-forms, but no DNA synthesis takes place.
Meiosis II
Prophase II* Chromosomes condense, the spindle forms, and the nuclear envelope disintegrates.
Metaphase II Individual chromosomes line up on the metaphase plate.
Anaphase II Sister chromatids separate and move as individual chromosomes toward the spindle poles.
Telophase II Chromosomes arrive at the spindle poles; the spindle breaks down and a nuclear envelope re-forms.
Cytokinesis The cytoplasm divides.
*Only in cells in which the spindle has broken down, chromosomes have relaxed, and the nuclear envelope has re-formed in telophase I. Other types of cells proceed directly to metaphase II after cytokinesis.
Table 2.2: Major events in each stage of meiosis