Gene Normal function Cancer in which gene is mutated
erbB Part of growth factor receptor Many types of cancer
fos Transcription factor Osteosarcoma and endometrial carcinoma
jun Transcription factor, cell cycle control Lung cancer, breast cancer
myc Transcription factor Lymphomas, leukemias, neuroblastoma
ras GTp binding and GTpase Many types of cancer
sis Growth factor Glioblastomas and other cancers
src Protein tyrosine kinase Many types of cancer
Table 23.4: Some oncogenes and functions of their corresponding proto-oncogenes