Chapter 1

Articles on ethical issues in genetics are preceded by an asterisk.

Suggested Readings

R1

*American Society of Human Genetics Board of Directors and the American College of Medical Genetics Board of Directors. 1995. Points to consider: ethical, legal, and psychosocial implications of genetic testing in children. American Journal of Human Genetics 57:1233–1241.

An official statement by two groups of professional geneticists on some of the ethical, legal, and psychological considerations in conducting genetic tests on children.

Drmanac, R. 2012. The ultimate genetic test. Science 336:1110–1112.

An editorial on the future of whole-genome sequencing.

Dunn, L. C. 1965. A Short History of Genetics. New York: McGraw-Hill.

An excellent history of major developments in the field of genetics.

Evenson, R. E., and D. Gollin. 2003. Assessing the impact of the Green Revolution, 1960–2000. Science 300:758–762.

Summarizes the effects of the Green Revolution on the improvement of crop productivity in developing countries.

Hedrick, P. W. 2003. Hopi Indians, “cultural” selection, and albinism. American Journal of Physical Anthropology 121:151–156.

A good discussion of the genetics and evolution of albinism in the Hopi Native Americans of the American Southwest.

Lamason, R. L., M. P. K. Mohideen, J. R. Mest, et al. 2005. SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans. Science 310:1782–1786.

A research report on the identification of a gene that affects pigmentation in humans.

Lander, E. S. 2011. Initial impact of the sequencing of the human genome. Nature 47:187–197.

A review of the effects and the future of the sequencing of the human genome, written on the 10-year anniversary of the unveiling of the first human genome sequence.

Lander, E. S., and R. A. Weinberg. 2000. Genomics: journey to the center of biology. Science 287:1777–1782.

A succinct history of genetics and, more specifically, genomics, written by two of the leaders of modern genetics.

Meredith, R. W., J. E. Janecka, J. Gatesy, et al. 2011. Impacts of the Cretaceous terrestrial revolution and KPg extinction on mammal diversification. Science 334:521–524.

A new evolutionary tree of all mammalian families based on DNA sequences from 26 genes.

Myocardial Infarction Genetics Consortium. 2009. Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nature Genetics 41:334–341.

A study of single-nucleotide polymorphisms revealing the presence of several genes that influence a predisposition to heart attacks. See other articles in the same issue of Nature Genetics.

*Nowlan, W. 2002. A rational view of insurance and genetic discrimination. Science 297:195.

A discussion of the use of genetic information for insurance purposes from the perspective of the insurance industry. An article by K. H. Rothenberg and S. F. Terry in this issue of Science presents an alternative view.

*Rosenberg, K., B. Fuller, M. Rothstein, et al. 1997. Genetic information and workplace: legislative approaches and policy challenges. Science 275:1755–1757.

Deals with the use of genetic information in employment.

*Shapiro, H. T. 1997. Ethical and policy issues of human cloning. Science 277:195–196.

A discussion of the ethics of human cloning.

Stubbe, H. 1972. History of Genetics: From Prehistoric Times to the Rediscovery of Mendel’s Laws. Translated by T. R. W. Waters. Cambridge, Mass.: MIT Press.

A good history of genetics, especially of pre-Mendelian genetics.

Sturtevant, A. H. 1965. A History of Genetics. New York: Harper & Row.

An excellent history of genetics.

Witkop, C. J., Jr., J. D. Niswander, D. R. Bergsma, et al. 2005. Tyrosinase positive oculocutaneous albinism among Zuni and the Brandywine triracial isolate: biochemical and clinical characteristics and fertility. American Journal of Physical Anthropology 36:397–405.

A biochemical analysis of albinism in the Zuni Native Americans.

Woolf, C. M., and F. C. Dukepoo. 1969. Hopi Indians, inbreeding, and albinism. Science 164:30–37.

A report on the incidence of albinism in the Hopi Native Americans and possible reasons for its high frequency.

Yi, Z., N. Garrison, O. Cohen-Barak, et al. 2003. 122.5-kilobase deletion of the P gene underlies the high prevalence of oculocutaneous albinism type 2 in the Navajo population. American Journal of Human Genetics 72(1): 62–72.

Genetic characterization of albinism in the Navaho Native Americans of the Southwest.