Articles on ethical issues in genetics are preceded by an asterisk.

Avery, O. T., C. M. MacLeod, and M. McCarty. 1944. Studies on the chemical nature of the substance inducing transformation of pneumococcal types. Journal of Experimental Medicine 79:137–158.

Avery, MacLeod, and McCarty’s description of their demonstration that the transforming principle is DNA.

Bernstein, B. E., M. Kamal, K. Lindblad-Toh, et al. 2005. Genomic maps and comparative analysis of histone modifications in humans and mouse. Cell 120:169–181.

A study of the genomic locations of histone modifications.

Crick, F. 1988. What Mad Pursuit: A Personal View of Scientific Discovery. New York: Basic Books.

Francis Crick’s personal account of the discovery of the structure of DNA.

Dickerson, R. E., H. R. Drew, B. N. Conner, et al. 1982. The anatomy of A-, B-, and Z-DNA. Science 216:475–485.

A review of differences in secondary structures of DNA.

Foltz, D. R., L. E. Jansen, A. O. Bailey, et al. 2009. Centromere-specific assembly of CENP-A nucleosomes is mediated by HJURP. Cell 137:472–484.

A discussion of the assembly of special chromatin at the centromere.

Greider, C. W., and E. H. Blackburn. 1996. Telomeres, telomerase, and cancer. Scientific American 274(2): 92–97.

An excellent review of telomeres and telomerase.

Griffith, F. 1928. The significance of pneumococcal types. Journal of Hygiene 27:113–159.

R7

Griffith’s original report on the transforming principle.

Ha, S. C., K. Lowenhaupt, A. Rich, et al. 2005. Crystal structure of a junction between B-DNA and Z-DNA reveals two extruded bases. Nature 437:1183–1186.

Reports an investigation into the three-dimensional configuration of a B-DNA molecule, part of which is flipped into the Z-DNA configuration.

Hagmann, M. 1999. How chromatin changes its shape. Science 285:1200–1203.

A report on how chromatin changes its shape in response to various genetic functions.

Hershey, A. D., and M. Chase. 1952. Independent functions of viral protein and nucleic acid in growth of bacteriophage. Journal of General Physiology 36:39–56.

Hershey and Chase’s original report on their well-known experiment with T2 bacteriophage.

Kornberg, R. D., and A. Klug. 1981. The nucleosome. Scientific American 244(2): 52–64.

A good review of basic chromatin structure and how it was discovered.

Koster, D. A., A. Crut, S. Shuman, et al. 2010. Cellular strategies for regulating DNA supercoiling: a single molecule perspective. Cell 142:519–530.

A review of how supercoiling within the cell is regulated.

Luger, K., A. W. Mäder, R. K. Richmond, et al. 1997. Crystal structure of the nucleosome core particle at 2.8 Å resolution. Nature 389:251–260.

A report on the detailed structure of the nucleosome as revealed by X-ray crystallography.

McEachern, M. J., A. Krauskopf, and E. H. Blackburn. 2000. Telomeres and their control. Annual Review of Genetics 34:331–358.

A review of telomere structure and control.

Miescher, F. 1871. On the chemical composition of pus cells. Hoppe-Seyler’s Med.-Chem. Untersuch. 4:441–460. Abridged and translated in M. L. Gabriel and S. Fogel, eds., Great Experiments in Biology, Englewood Cliffs, N.J.: Prentice Hall, 1955.

An abridged and translated version of Miescher’s original paper chemically characterizing DNA.

Mirsky, A. E. 1968. The discovery of DNA. Scientific American 218(6): 78–88.

A good account of the discovery of DNA structure.

Palm, W., and T. de Lange. 2008. How shelterin protects mammalian telomeres. Annual Review of Genetics 42:301–334.

A review of shelterin, a protein that protects mammalian telomeres.

Rasmussen, M., Y. Li, S. Lindgreen, et al. 2010. Ancient human genome sequence of an extinct Palaeo-Eskimo. Nature 463:757–873.

Report of the sequencing of the genome of a 4000-year-old man from Greenland.

Rich, A., A. Nordheim, and A. H.-J. Wang. 1984. The chemistry and biology of left-handed Z-DNA. Annual Review of Biochemistry 53:791–846.

A good review article on the structure and possible function of Z-DNA.

Rich, A., and S. Zhang. 2003. Z-DNA: the long road to biological function. Nature Reviews Genetics 4:566–572.

An excellent review of a possible function for Z-DNA by one of the leading researchers in the field.

Richmond, T. J., and C. A. Davey. 2003. The structure of DNA in the nucleosome core. Nature 423:145–150.

A fairly technical article that gives a current account of DNA structure within the nucleosome core particle.

Sayre, A. 2000. Rosalind Franklin and DNA. New York: W. W. Norton.

A biography of Rosalind Franklin, who played a major role in the discovery of DNA.

Watson, J. D. 1968. The Double Helix. New York: Atheneum.

An excellent account of Watson and Crick’s discovery of DNA.

Watson, J. D., and F. C. Crick. 1953. Molecular structure of nucleic acids: a structure for deoxyribose nucleic acids. Nature 171:737–738.

The original paper in which Watson and Crick first presented their new structure for DNA.

Wolffe, A. P. 1998. Chromatin: Structure and Function, 3d ed. San Diego: Academic Press.

A detailed review of chromatin structure and function.

Zakian, V. A. 1995. Telomeres: beginning to understand the ends. Science 270:1601–1606.

An excellent review of telomere structure and function.

Zimmerman, S. B. 1982. The three-dimensional structure of DNA. Annual Review of Biochemistry 51:395–427.

A review of the different secondary structures that DNA can assume.