24.Many cancer cells are immortal (will divide indefinitely) because they have mutations that allow telomerase to be expressed. How might this knowledge be used to design anticancer drugs?

25.Bloom syndrome is an autosomal recessive disease that exhibits haploinsufficiency. A recent survey showed that people heterozygous for mutations at the BLM locus are at increased risk of colon cancer. Suppose that you are a genetic counselor. A young woman whose mother has Bloom syndrome is referred to you. The young woman’s father has no family history of Bloom syndrome, and she asks whether she is likely to experience any other health problems associated with her family history of Bloom syndrome. What advice would you give her?

26.Radiation is known to cause cancer, yet radiation is often used as treatment for some types of cancer. How can radiation be a contributor to both the cause and the treatment of cancer?

27.Imagine that you discover a large family in which bladder cancer is inherited as an autosomal dominant trait. Briefly outline a series of studies that you might conduct to identify the gene that causes bladder cancer in this family.