Divisions of Genetics

The study of genetics consists of three major subdisciplines: transmission genetics, molecular genetics, and population genetics (Figure 1.6). Transmission genetics (also known as classical genetics) encompasses the basic principles of heredity and how traits are passed from one generation to the next. This subdiscipline addresses the relation between chromosomes and heredity, the arrangement of genes on chromosomes, and gene mapping. Here, the focus is on the individual organism—how an individual inherits its genetic makeup and how it passes its genes to the next generation.

image
Figure 1.6: Genetics can be subdivided into three interrelated fields.
[Top left: Juniors Bildarchiv/Alamy. Top right: Martin McCarthy/Getty Images. Bottom: Stuart Wilson/Science Source.]

Molecular genetics concerns the chemical nature of the gene itself: how genetic information is encoded, replicated, and expressed. It includes the cellular processes of replication, transcription, and translation (by which genetic information is transferred from one molecule to another) and of gene regulation (the processes that control the expression of genetic information). The focus in molecular genetics is the gene—its structure, organization, and function.

Population genetics explores the genetic composition of groups of individuals of the same species (populations) and how that composition changes over time and space. Because evolution is genetic change, population genetics is fundamentally the study of evolution. The focus of this subdiscipline is the group of genes found in a population.

The division of the study of genetics into these three subdisciplines is convenient and traditional, but we should recognize that these subdisciplines overlap and that each one can be further divided into a number of more specialized fields, such as chromosomal genetics, biochemical genetics, quantitative genetics, and so forth. Alternatively, the study of genetics can be subdivided by organism (fruit-fly, corn, or bacterial genetics), and each of these organisms can be studied at the level of transmission, molecular, or population genetics. Modern genetics is an extremely broad field, encompassing many interrelated subdisciplines and specializations. image TRY PROBLEM 17