TRICLOSAN—A COMPOUND OF EMERGING CONCERN?
Background: Triclosan (2,4,4’–trichloro-2’-hydroxydiphenyl ether) is a synthetic compound used as a broad-spectrum antimicrobial agent in a variety of consumer products such as toothpaste, antibacterial hand soaps, deodorants, and detergents. It has also been incorporated into plastics such as children’s toys and kitchen utensils, as well as many other industrial and household items. Triclosan was first registered as a pesticide in 1969. According to one estimate, the annual use of triclosan is more than 300 000 kg/year.
Triclosan’s efficacy and value are under question. The Canadian Medical Association does not consider triclosan either necessary or efficacious in personal care products (see www.cma.ca/en/Pages/cma_default.aspx). Physicians are particularly concerned about the development of antibiotic resistance. They also assert that soap and alcohol-based products are just as effective in preventing infection. In addition, there are concerns about the impact of triclosan and its breakdown products on the environment.
Case: You have been assigned the task of critically evaluating the research on triclosan and developing a position paper for the future use and regulation of this chemical.