![](tymoczko_ch13_fig_11.jpg)
Figure 13.11 The phospholipase C reaction. Phospholipase C cleaves the membrane lipid phosphatidylinositol 4,5-bisphosphate into two second messengers: diacylglycerol, which remains in the membrane, and inositol 1,4,5-trisphosphate, which diffuses away from the membrane.