Figure 13.6 
Adenylate cyclase activation. (A) Adenylate cyclase is a membrane protein with two large intracellular domains (red and orange) that contain the catalytic apparatus. (B) The structure of the complex between Gα in its GTP form bound to a catalytic fragment of adenylate cyclase. Notice that the surface of Gα that had been bound to the bg dimer (Figure 13.5) now binds adenylate cyclase.
Adenylate cyclase activation. (A) Adenylate cyclase is a membrane protein with two large intracellular domains (red and orange) that contain the catalytic apparatus. (B) The structure of the complex between Gα in its GTP form bound to a catalytic fragment of adenylate cyclase. Notice that the surface of Gα that had been bound to the bg dimer (Figure 13.5) now binds adenylate cyclase.