First Treaty of Fort Laramie negotiated.

Great Sioux Uprising (Santee Uprising) kills 1,000 settlers.

Sand Creek massacre kills several hundred Indians.

Treaty of Medicine Lodge negotiated.

Second Treaty of Fort Laramie negotiated.

Hunters begin to decimate bison herds.

Gold discovered in Black Hills.

Battle of the Little Big Horn destroys Custer's army.

Sitting Bull surrenders.

Frederick Jackson Turner presents “frontier thesis.”