Part I THE MOLECULAR DESIGN OF LIFE

1

Biochemistry: An Evolving Science

2

Protein Composition and Structure

3

Exploring Proteins and Proteomes

4

DNA, RNA, and the Flow of Genetic Information

5

Exploring Genes and Genomes

6

Exploring Evolution and Bioinformatics

7

Hemoglobin: Portrait of a Protein in Action

8

Enzymes: Basic Concepts and Kinetics

9

Catalytic Strategies

10

Regulatory Strategies

11

Carbohydrates

12

Lipids and Cell Membranes

13

Membrane Channels and Pumps

14

Signal-Transduction Pathways

Part II TRANSDUCING AND STORING ENERGY

15

Metabolism: Basic Concepts and Design

16

Glycolysis and Gluconeogenesis

17

The Citric Acid Cycle

18

Oxidative Phosphorylation

19

The Light Reactions of Photosynthesis

20

The Calvin Cycle and the Pentose Phosphate Pathway

21

Glycogen Metabolism

22

Fatty Acid Metabolism

23

Protein Turnover and Amino Acid Catabolism

Part III SYNTHESIZING THE MOLECULES OF LIFE

24

The Biosynthesis of Amino Acids

25

Nucleotide Biosynthesis

26

The Biosynthesis of Membrane Lipids and Steroids

27

The Integration of Metabolism

28

DNA Replication, Repair, and Recombination

29

RNA Synthesis and Processing

30

Protein Synthesis

31

The Control of Gene Expression in Prokaryotes

32

The Control of Gene Expression in Eukaryotes

Part IV RESPONDING TO ENVIRONMENTAL CHANGES

33

Sensory Systems

34

The Immune System

35

Molecular Motors

36

Drug Development